Managing CDH1 Cancer Risks in a Child: Complex Decision Making in a Family With Hereditary Diffuse Gastric Cancer.

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作者： Nihat Bugra,Agaoglu ^[1] ; Ozden Hatirnaz,Ng ^[2] ; Itir Ebru,Zemheri ^[3] ; Busra,Unal ^[4] ; Nelgin,Gerenli ^[5] ; Ilkay,Tosun ^[3] ; Hulya,Yazıcı ^[6] ; Ugur,Ozbek ^[7] ; Junne,Kamihara ^[8] ; Huma Q,Rana ^[9]

作者单位： Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Department of Medical Genetics, Division of Cancer Genetics, Umraniye Training and Research Hospital, Istanbul, Turkey.;Frankfurter Institut für Klinische Krebsforschung IKF, Frankfurt, Germany. ^[1] Department of Medical Biology, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.;Department of Medical Genetics, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.;Acibadem University Rare Diseases and Orphan Drugs Application and Research Center, Istanbul, Turkey. ^[2] Department of Pathology, Umraniye Training and Research Hospital, Istanbul, Turkey. ^[3] Department of Medical Genetics, Division of Cancer Genetics, Umraniye Training and Research Hospital, Istanbul, Turkey. ^[4] Department of Pediatric Gastroenterology, Umraniye Training and Research Hospital, Istanbul, Turkey. ^[5] Oncology Institute, Istanbul University, Istanbul, Turkey.;Department of Medical Genetics and Biology, Medical School, Istanbul Health and Technology University, Istanbul, Turkey. ^[6] Department of Medical Genetics, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.;Izmir Biomedicine and Genome Center (IBG), Izmir, Turkey. ^[7] Department of Pediatric Hematology-Oncology, Boston Children's Hospital, Boston, Massachusetts, USA.;Department of Pediatric Hematology/Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Harvard Medical School, Boston, Massachusetts, USA. ^[8] Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.;Harvard Medical School, Boston, Massachusetts, USA.;Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. ^[9]

关键词 CDH1 adolescent diffuse gastric cancer pediatric young adult