3D Scaffold-Based Culture System Enhances Preclinical Evaluation of Natural Killer Cell Therapy in A549 Lung Cancer Cells.

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第一作者： Eun Hee,Han

第一单位： Biopharmaceutical Research Center, Ochang Institute of Biological and Environmental Science, Korea Basic Science Institute (KBSI), Cheongju 28119, Republic of Korea.;Korea University of Science and Technology (UST), Daejeon 34113, Republic of Korea.

作者： Eun Hee,Han ^[1] ; Sun-Hee,Cho ^[2] ; Sang Nam,Lee ^[3] ; Mi Young,Cho ^[4] ; Hyunseung,Lee ^[2] ; Soo Yun,Lee ^[5] ; Chau,Ngoc Thi Tran ^[6] ; Hye Sun,Park ^[2] ; Jin Young,Min ^[2] ; Hye Min,Kim ^[1] ; Min Sung,Park ^[1] ; Tae-Don,Kim ^[5] ; Yong Taik,Lim ^[3] ; Kwan Soo,Hong ^[6]

作者单位： Biopharmaceutical Research Center, Ochang Institute of Biological and Environmental Science, Korea Basic Science Institute (KBSI), Cheongju 28119, Republic of Korea.;Korea University of Science and Technology (UST), Daejeon 34113, Republic of Korea. ^[1] Biopharmaceutical Research Center, Ochang Institute of Biological and Environmental Science, Korea Basic Science Institute (KBSI), Cheongju 28119, Republic of Korea. ^[2] SKKU Advanced Institute of Nanotechnology (SAINT) and School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea. ^[3] Biopharmaceutical Research Center, Ochang Institute of Biological and Environmental Science, Korea Basic Science Institute (KBSI), Cheongju 28119, Republic of Korea.;SKKU Advanced Institute of Nanotechnology (SAINT) and School of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Republic of Korea. ^[4] Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea. ^[5] Biopharmaceutical Research Center, Ochang Institute of Biological and Environmental Science, Korea Basic Science Institute (KBSI), Cheongju 28119, Republic of Korea.;Department of Chemistry, Chung-Ang University, Seoul 06974, Republic of Korea. ^[6]

关键词 anticancer drug resistance cell-based immunotherapy epithelial?mesenchymal transition scaffold-based cell culture three-dimensional cell culture model

主题词人类(Humans);杀伤细胞, 天然(Killer Cells, Natural);肺肿瘤(Lung Neoplasms);组织支架(Tissue Scaffolds);生物相容性材料(Biocompatible Materials);抗肿瘤药(Antineoplastic Agents);材料试验(Materials Testing);粒子大小(Particle Size);细胞增殖(Cell Proliferation);上皮-间质转化(Epithelial-Mesenchymal Transition);动物(Animals);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);共同培养技术(Coculture Techniques)

DOI 10.1021/acsabm.4c00800

PMID 39392900

发布时间 2024-11-18

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ACS applied bio materials

2024年7卷11期

7194-7206页

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3D Scaffold-Based Culture System Enhances Preclinical Evaluation of Natural Killer Cell Therapy in A549 Lung Cancer Cells.

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3D Scaffold-Based Culture System Enhances Preclinical Evaluation of Natural Killer Cell Therapy in A549 Lung Cancer Cells.

ACS applied bio materials

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