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Epigenetic reprogramming in pediatric gliomas: from molecular mechanisms to therapeutic implications.

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第一作者： Santiago,Haase

第一单位： Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, Biomedical Science Research Building, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Biointerfaces Institute, BioInnovations in Brain Cancer Initiative (BIBC), University of Michigan, Ann Arbor, MI, 48109, USA.

作者： Santiago,Haase ^[1] ; Stephen,Carney ^[1] ; Maria Luisa,Varela ^[1] ; Devarshi,Mukherji ^[1] ; Ziwen,Zhu ^[1] ; Yingxiang,Li ^[1] ; Felipe J,Nuñez ^[1] ; Pedro R,Lowenstein ^[1] ; Maria G,Castro ^[2]

作者单位： Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, Biomedical Science Research Building, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Biointerfaces Institute, BioInnovations in Brain Cancer Initiative (BIBC), University of Michigan, Ann Arbor, MI, 48109, USA. ^[1] Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, Biomedical Science Research Building, Ann Arbor, MI 48109, USA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Biointerfaces Institute, BioInnovations in Brain Cancer Initiative (BIBC), University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: mariacas@med.umich.edu. ^[2]

关键词 H3G34R H3K27M diffuse hemispheric glioma (DHG)diffuse midline glioma (DMG)pediatric diffuse high-grade gliomas (pHGGs)