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Low-dose titrated amitriptyline as second-line treatment for adults with irritable bowel syndrome in primary care: the ATLANTIS RCT.

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第一作者： Alexandra,Wright-Hughes

第一单位： Clinical Trial Research Unit, Leeds Institute of Clinical Trials Research, School of Medicine, University of Leeds, Leeds, UK.

作者： Alexandra,Wright-Hughes ^[1] ; Alexander C,Ford ^[2] ; Sarah L,Alderson ^[3] ; Pei Loo,Ow ^[1] ; Matthew J,Ridd ^[4] ; Robbie,Foy ^[3] ; Felicity L,Bishop ^[5] ; Matthew,Chaddock ^[6] ; Heather,Cook ^[1] ; Deborah,Cooper ^[3] ; Catherine,Fernandez ^[1] ; Elspeth A,Guthrie ^[3] ; Suzanne,Hartley ^[1] ; Amy,Herbert ^[4] ; Daniel,Howdon ^[3] ; Delia P,Muir ^[1] ; Sonia,Newman ^[7] ; Christopher A,Taylor ^[1] ; Emma J,Teasdale ^[5] ; Ruth,Thornton ^[7] ; Hazel A,Everitt ^[7] ; Amanda J,Farrin ^[1]

作者单位： Clinical Trial Research Unit, Leeds Institute of Clinical Trials Research, School of Medicine, University of Leeds, Leeds, UK. ^[1] Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK.;Leeds Gastroenterology Institute, St. James's University Hospital, Leeds, UK. ^[2] Leeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, UK. ^[3] Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. ^[4] Centre for Clinical and Community Applications of Health Psychology, School of Psychology, University of Southampton, Southampton, UK. ^[5] Let's Cure IBS, Leeds, UK. ^[6] Primary Care Research Centre, Faculty of Medicine, University of Southampton, Southampton, UK. ^[7]

关键词 ABDOMINAL PAIN AMITRIPTYLINE GENERAL PRACTICE IRRITABLE BOWEL SYNDROME OUTCOME ASSESSMENT RANDOMISED CONTROLLED TRIAL