FL118 Enhances Therapeutic Efficacy in Colorectal Cancer by Inhibiting the Homologous Recombination Repair Pathway through Survivin-RAD51 Downregulation.

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作者： Jungyoun,Kim ^[1] ; Yeyeong,Jeong ^[1] ; You Me,Shin ^[1] ; Sung Eun,Kim ^[1] ; Sang Joon,Shin ^[2]

作者单位： Department of Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.;Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea. ^[1] Songdang Institute for Cancer Research, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.;Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul 03722, Republic of Korea. ^[2]

关键词 DNA damage FL118 RAD51 colorectal cancer irinotecan resistance survivin

DOI 10.3390/cancers16193385

PMID 39410005

发布时间 2024-10-19

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