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Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells.

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第一作者： Chloe G,Myers

第一单位： Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.

作者： Chloe G,Myers ^[1] ; Hema,Viswambharan ^[1] ; Natalie J,Haywood ^[1] ; Katherine,Bridge ^[1] ; Samuel,Turvey ^[1] ; Tom,Armstrong ^[1] ; Lydia,Lunn ^[2] ; Paul J,Meakin ^[1] ; Karen E,Porter ^[1] ; Eva M,Clavane ^[1] ; David J,Beech ^[3] ; Richard M,Cubbon ^[3] ; Stephen B,Wheatcroft ^[1] ; Martin J,McPhillie ^[2] ; Tarik,Issad ^[4] ; Colin Wg,Fishwick ^[2] ; Mark T,Kearney ^[5] ; Katie J,Simmons ^[6]

作者单位： Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom. ^[1] Department of Chemistry University of Leeds, Leeds, United Kingdom. ^[2] Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom; National Institute for Health and Care Research Leeds Biomedical Research Centre, Leeds, United Kingdom. ^[3] Université Paris Cité, CNRS, INSERM, Institut Cochin, F-75014, Paris, France. ^[4] Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom; National Institute for Health and Care Research Leeds Biomedical Research Centre, Leeds, United Kingdom. Electronic address: m.t.kearney@leeds.ac.uk. ^[5] School of Biomedical Sciences, Faculty of Biological Sciences & Astbury Centre, University of Leeds, United Kingdom. ^[6]

关键词 Diabetes Hybrid receptors Insulin receptors Insulin-like growth factor-1 receptors Small molecule