Deep brain stimulation mitigates memory deficits in a rodent model of traumatic brain injury.

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第一作者： Thallita K,Rabelo

第一单位： Sunnybrook Research Institute, Toronto, ON, Canada.

作者： Thallita K,Rabelo ^[1] ; Ana Carolina P,Campos ^[1] ; Thiago H,Almeida Souza ^[1] ; Faiza,Mahmud ^[2] ; Milos R,Popovic ^[3] ; Luciene,Covolan ^[4] ; Victor H C,Betta ^[4] ; Leodante,DaCosta ^[5] ; Nir,Lipsman ^[6] ; Mustansir,Diwan ^[1] ; Clement,Hamani ^[7]

作者单位： Sunnybrook Research Institute, Toronto, ON, Canada. ^[1] Sunnybrook Research Institute, Toronto, ON, Canada; Institute of Biomaterials and Biomedical Engineering University of Toronto, ON, Canada. ^[2] Institute of Biomaterials and Biomedical Engineering University of Toronto, ON, Canada; Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada. ^[3] Department of Physiology, Federal University of São Paulo, São Paulo, SP, Brazil. ^[4] Sunnybrook Research Institute, Toronto, ON, Canada; Division of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. ^[5] Sunnybrook Research Institute, Toronto, ON, Canada; Division of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Harquail Centre for Neuromodulation, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada. ^[6] Sunnybrook Research Institute, Toronto, ON, Canada; Division of Neurosurgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada; Harquail Centre for Neuromodulation, Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada. Electronic address: clement.hamani@sunnybrook.ca. ^[7]

关键词 BDNF Deep brain stimulation Memory Neuroinflammation Traumatic brain injury

主题词动物(Animals);深部脑刺激法(Deep Brain Stimulation);男(雄)性(Male);记忆障碍(Memory Disorders);大鼠(Rats);疾病模型, 动物(Disease Models, Animal);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);脑源性神经营养因子(Brain-Derived Neurotrophic Factor);迷宫学习(Maze Learning)

DOI 10.1016/j.brs.2024.10.006

PMID 39419474

发布时间 2024-12-20

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Brain stimulation

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Deep brain stimulation mitigates memory deficits in a rodent model of traumatic brain injury.

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Deep brain stimulation mitigates memory deficits in a rodent model of traumatic brain injury.

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