The causality between rheumatoid arthritis and postural deformities: bidirectional Mendelian randomization study and mediation analysis.

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第一作者： Piqian,Zhao

第一单位： Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Beijing, China.;Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.;Department of Orthopedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, Jiangsu, China.

作者： Piqian,Zhao ^[1] ; Zhe,Chen ^[2] ; Ya,Wen ^[3] ; Hongtao,Zhang ^[4] ; Liangyuan,Wen ^[5] ; Zijie,Pei ^[5]

作者单位： Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Beijing, China.;Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.;Department of Orthopedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, Jiangsu, China. ^[1] Department of Thoracic Surgery, The Fourth Affiliated Hospital of Soochow University, Suzhou, China. ^[2] Capital Medical University School of Biomedical Engineering, Beijing, China. ^[3] Department of Orthopedics, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, Jiangsu, China. ^[4] Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Beijing, China.;Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. ^[5]

关键词 Mendelian randomization flat foot hallux valgus postural deformities rheumatoid arthritis scoliosis

主题词人类(Humans);关节炎, 类风湿(Arthritis, Rheumatoid);孟德尔随机化分析(Mendelian Randomization Analysis);脊柱侧凸(Scoliosis);拇外翻(Hallux Valgus);扁平足(Flatfoot);疾病遗传易感性(Genetic Predisposition to Disease)

DOI 10.3389/fimmu.2024.1453685

PMID 39421746

发布时间 2024-10-19

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