首页> eLife> Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states.

Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states.

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第一作者： Revathi,Balasubramanian

第一单位： Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.

作者： Revathi,Balasubramanian ^[1] ; Krishnakumar,Kizhatil ^[2] ; Taibo,Li ^[3] ; Nicholas,Tolman ^[4] ; Aakriti,Bhandari ^[5] ; Graham,Clark ^[2] ; Violet,Bupp-Chickering ^[1] ; Ruth A,Kelly ^[6] ; Sally,Zhou ^[7] ; John,Peregrin ^[1] ; Marina,Simón ^[1] ; Christa,Montgomery ^[1] ; W Daniel,Stamer ^[6] ; Jiang,Qian ^[8] ; Simon W M,John ^[9]

作者单位： Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States. ^[1] Department of Ophthalmology and Visual Sciences, The Ohio State University Medical Center, Columbus, United States. ^[2] Department of Molecular Biology and Genetics, Johns Hopkins University, Baltimore, United States. ^[3] Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.;Graduate School of Biomedical Sciences, Tufts University School of Medicine, Boston, United States. ^[4] Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.;Neuroscience Graduate Program, University of Utah, Salt Lake City, United States. ^[5] Department of Ophthalmology, Duke University, Durham, United States. ^[6] Department of Ophthalmology, Columbia University Irving Medical Center, New York, United States.;SUNY Downstate Health Sciences University, New York, United States. ^[7] Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, United States. ^[8] Zuckerman Mind Brain Behavior Institute, Columbia University, New York, United States. ^[9]

关键词 Schlemm's canal cell biology glaucoma anterior segment mouse single cell transcriptomics trabecular meshwork