CRISPR/Cas9-mediated generation of a human induced pluripotent stem cell line with PRPF6 c.2699 G > A mutation to model retinitis pigmentosa.

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作者： Yuqin,Liang ^[1] ; Xihao,Sun ^[1] ; Hang,Chen ^[2] ; Zekai,Cui ^[3] ; Jianing,Gu ^[4] ; Chunwen,Duan ^[3] ; Shengru,Mao ^[4] ; Yuexi,Chen ^[5] ; Xiaoxue,Li ^[3] ; Siqi,Xiong ^[6] ; Jiansu,Chen ^[7]

作者单位： Aier Eye Institute, Changsha 410015, China; Eye Center of Xiangya Hospital, Central South University, Changsha 410008, China. ^[1] Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China. ^[2] Aier Eye Institute, Changsha 410015, China; Aier Academy of Ophthalmology, Central South University, Changsha 410015, China. ^[3] Aier Eye Institute, Changsha 410015, China. ^[4] Aier Eye Hospital, Jinan University, Guangzhou 510632, China. ^[5] Eye Center of Xiangya Hospital, Central South University, Changsha 410008, China. Electronic address: petersage1221@126.com. ^[6] Aier Eye Institute, Changsha 410015, China; Aier Academy of Ophthalmology, Central South University, Changsha 410015, China; Aier Eye Hospital, Jinan University, Guangzhou 510632, China. Electronic address: chenjiansu2000@163.com. ^[7]

主题词诱导多能干细胞(Induced Pluripotent Stem Cells);色素性视网膜炎(Retinitis Pigmentosa);人类(Humans);突变(Mutation);细胞系(Cell Line)

DOI 10.1016/j.scr.2024.103581

PMID 39423676

发布时间 2024-12-13

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Stem cell research

2024年81卷

103581页

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CRISPR/Cas9-mediated generation of a human induced pluripotent stem cell line with PRPF6 c.2699 G > A mutation to model retinitis pigmentosa.

Stem cell research

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CRISPR/Cas9-mediated generation of a human induced pluripotent stem cell line with PRPF6 c.2699 G &gt; A mutation to model retinitis pigmentosa.

Stem cell research

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Stem cell research

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CRISPR/Cas9-mediated generation of a human induced pluripotent stem cell line with PRPF6 c.2699 G > A mutation to model retinitis pigmentosa.