Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model.

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第一作者： Amélie M,Borie

第一单位： Institut de Génomique Fonctionnelle, Department of Neuroscience, Stress Hormones and Plasticity Unit, University of Montpellier, INSERM, CNRS, 34090 Montpellier, France.

作者： Amélie M,Borie ^[1] ; Yann,Dromard ^[1] ; Prabahan,Chakraborty ^[1] ; Pierre,Fontanaud ^[1] ; Emilie M,Andre ^[2] ; Amaury,François ^[1] ; Pascal,Colson ^[3] ; Françoise,Muscatelli ^[4] ; Gilles,Guillon ^[1] ; Michel G,Desarménien ^[1] ; Freddy,Jeanneteau ^[5]

作者单位： Institut de Génomique Fonctionnelle, Department of Neuroscience, Stress Hormones and Plasticity Unit, University of Montpellier, INSERM, CNRS, 34090 Montpellier, France. ^[1] Institut de Génomique Fonctionnelle, Department of Neuroscience, Stress Hormones and Plasticity Unit, University of Montpellier, INSERM, CNRS, 34090 Montpellier, France; Département de Maieutique, University of Montpellier, 34090 Montpellier, France. ^[2] Institut de Génomique Fonctionnelle, Department of Neuroscience, Stress Hormones and Plasticity Unit, University of Montpellier, INSERM, CNRS, 34090 Montpellier, France; Department of Anesthesiology and Critical Care Medicine, Arnaud de Villeneuve Academic Hospital, Montpellier 34090 Montpellier, France. ^[3] Institut de Neurobiologie de la Méditerranée, INSERM, University of Aix-Marseille, 13273 Marseille, France. ^[4] Institut de Génomique Fonctionnelle, Department of Neuroscience, Stress Hormones and Plasticity Unit, University of Montpellier, INSERM, CNRS, 34090 Montpellier, France. Electronic address: freddy.jeanneteau@igf.cnrs.fr. ^[5]

关键词 Magel2 Pader-Willi autism optogenetic oxytocin photometry social somatostatin treatment vasopressin

主题词动物(Animals);疾病模型, 动物(Disease Models, Animal);小鼠(Mice);神经元(Neurons);社会行为(Social Behavior);孤独性障碍(Autistic Disorder);催产素(Oxytocin);受体, 催产素(Receptors, Oxytocin);神经肽类(Neuropeptides);男(雄)性(Male);血管升压素类(Vasopressins);生长抑素(Somatostatin);隔核(Septal Nuclei);信号传导(Signal Transduction);小鼠, 近交C57BL(Mice, Inbred C57BL)

DOI 10.1016/j.xcrm.2024.101781

PMID 39423809

发布时间 2024-12-01

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Cell reports. Medicine

2024年5卷11期

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Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model.

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Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model.

Cell reports. Medicine

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