Strain-specific differences in reovirus infection of murine macrophages segregate with polymorphisms in viral outer-capsid protein σ3.

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作者： Kay L,Fiske ^[1] ; Pamela H,Brigleb ^[2] ; Luzmariel Medina,Sanchez ^[3] ; Reinhard,Hinterleitner ^[4] ; Gwen M,Taylor ^[1] ; Terence S,Dermody ^[5]

作者单位： Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.;Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA. ^[1] Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.;Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. ^[2] Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.;Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.;Graduate Program in Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. ^[3] Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.;Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. ^[4] Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.;Institute of Infection, Inflammation, and Immunity, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.;Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. ^[5]

关键词 PirB capsid protein σ3 celiac disease loss of oral tolerance macrophages reassortant viruses reovirus