Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces.-论文-万方医学网

作者： Patrizia,Romani ^[1] ; Giada,Benedetti ^[1] ; Martina,Cusan ^[1] ; Mattia,Arboit ^[2] ; Carmine,Cirillo ^[3] ; Xi,Wu ^[4] ; Georgia,Rouni ^[5] ; Vassiliki,Kostourou ^[5] ; Mariaceleste,Aragona ^[6] ; Costanza,Giampietro ^[7] ; Paolo,Grumati ^[8] ; Graziano,Martello ^[2] ; Sirio,Dupont ^[9]

作者单位： Department of Molecular Medicine, University of Padova, Padova, Italy. ^[1] Department of Biology, University of Padova, Padova, Italy. ^[2] Telethon Institute of Genetics and Medicine, Pozzuoli, Italy. ^[3] Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland. ^[4] Institute for Bioinnovation, Biomedical Sciences Research Centre "Alexander Fleming", Athens, Greece. ^[5] Novo Nordisk Foundation Center for Stem Cell Medicine (ReNEW), University of Copenhagen, Copenhagen, Denmark. ^[6] Department of Mechanical and Process Engineering, ETH Zurich, Zurich, Switzerland.;Swiss Federal Laboratories for Materials Science and Technology, Dübendorf, Switzerland. ^[7] Telethon Institute of Genetics and Medicine, Pozzuoli, Italy.;Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy. ^[8] Department of Molecular Medicine, University of Padova, Padova, Italy. sirio.dupont@unipd.it. ^[9]

主题词动物(Animals);动力传导, 细胞(Mechanotransduction, Cellular);动力蛋白质类(Dynamins);线粒体(Mitochondria);小鼠(Mice);肽延伸因子(Peptide Elongation Factors);细胞增殖(Cell Proliferation);人类(Humans);细胞外基质(Extracellular Matrix);细胞核(Cell Nucleus);磷酰化(Phosphorylation);肝细胞(Hepatocytes);NF-E2相关因子2(NF-E2-Related Factor 2);肌动蛋白类(Actins);肌动球蛋白(Actomyosin);男(雄)性(Male);线粒体蛋白质类(Mitochondrial Proteins);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);转录因子(Transcription Factors);肝(Liver)

DOI 10.1038/s41556-024-01527-3

PMID 39433949

发布时间 2024-12-15

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Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces.

Nature cell biology

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Mitochondrial mechanotransduction through MIEF1 coordinates the nuclear response to forces.

Nature cell biology

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Nature cell biology

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