DNA-PK inhibition shows differential radiosensitization in orthotopic GBM PDX models based on DDR pathway deficits.

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第一作者： Sonja,Dragojevic

第一单位： Mayo Clinic, Rochester, Minnesota, United States.

作者： Sonja,Dragojevic ^[1] ; Emily J,Smith ^[1] ; Michael S,Regan ^[2] ; Sylwia A,Stopka ^[3] ; Gerard,Baquer ^[2] ; Zhiyi,Xue ^[1] ; Wenjuan,Zhang ^[4] ; Margaret A,Connors ^[1] ; Jake A,Kloeber ^[5] ; Zeng,Hu ^[5] ; Katrina K,Bakken ^[5] ; Lauren L,Ott ^[1] ; Brett L,Carlson ^[6] ; Danielle M,Burgenske ^[5] ; Paul A,Decker ^[6] ; Shulan,Tian ^[7] ; Shiv K,Gupta ^[5] ; Daniel J,Laverty ^[8] ; Jeanette E,Eckel-Passow ^[5] ; William F,Elmquist ^[4] ; Nathalie Y R,Agar ^[9] ; Zachary D,Nagel ^[8] ; Jann N,Sarkaria ^[5] ; Cameron M,Callaghan ^[5]

作者单位： Mayo Clinic, Rochester, Minnesota, United States. ^[1] Brigham and Women's Hospital, Boston, MA, United States. ^[2] Brigham and Women's Hospital, Boston, United States. ^[3] University of Minnesota, Minneapolis, MN, United States. ^[4] Mayo Clinic, Rochester, MN, United States. ^[5] Mayo Clinic, Rochester, United States. ^[6] Mayo Clinic, United States. ^[7] Harvard T.H. Chan School of Public Health, Boston, MA, United States. ^[8] Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. ^[9]

DOI 10.1158/1535-7163.MCT-24-0003

PMID 39440433

发布时间 2024-11-06

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Molecular cancer therapeutics

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DNA-PK inhibition shows differential radiosensitization in orthotopic GBM PDX models based on DDR pathway deficits.

Molecular cancer therapeutics

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DNA-PK inhibition shows differential radiosensitization in orthotopic GBM PDX models based on DDR pathway deficits.

Molecular cancer therapeutics

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Molecular cancer therapeutics

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