Single-cell transcriptome profiling identifies the activation of type I interferon signaling in ossified posterior longitudinal ligament.

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第一作者： Xiao,Liu

第一单位： Department of Orthopedics and Beijing Key Laboratory of Spinal Disease Research, Peking University Third Hospital, Beijing, 100191, China.

作者： Xiao,Liu ^[1] ; Lei,Zhang ^[2] ; Ge,Wang ^[2] ; Wei,Zhao ^[2] ; Chen,Liang ^[1] ; Youzhi,Tang ^[2] ; Yenan,Fu ^[2] ; Bo,Liu ^[2] ; Jing,Zhang ^[2] ; Xiaoguang,Liu ^[3] ; Hongquan,Zhang ^[4] ; Yu,Yu ^[5]

作者单位： Department of Orthopedics and Beijing Key Laboratory of Spinal Disease Research, Peking University Third Hospital, Beijing, 100191, China. ^[1] Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Molecular Oncology and International Cancer Institute, Peking University Health Science Center, Beijing, 100191, China. ^[2] Department of Orthopedics and Beijing Key Laboratory of Spinal Disease Research, Peking University Third Hospital, Beijing, 100191, China. xglius@vip.sina.com. ^[3] Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Molecular Oncology and International Cancer Institute, Peking University Health Science Center, Beijing, 100191, China. hongquan.zhang@bjmu.edu.cn. ^[4] Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, State Key Laboratory of Molecular Oncology and International Cancer Institute, Peking University Health Science Center, Beijing, 100191, China. yuyu@bjmu.edu.cn. ^[5]

关键词 IFN signaling ossification osteogenic differentiation posterior longitudinal ligament

主题词人类(Humans);信号传导(Signal Transduction);干扰素Ⅰ型(Interferon Type I);后纵韧带骨化(Ossification of Posterior Longitudinal Ligament);基因表达谱(Gene Expression Profiling);单细胞分析(Single-Cell Analysis);骨生成(Osteogenesis);受体, 干扰素αβ(Receptor, Interferon alpha-beta);男(雄)性(Male);女(雌)性(Female);细胞分化(Cell Differentiation);中年人(Middle Aged)

DOI 10.1007/s11684-024-1075-5

PMID 39441507

发布时间 2024-12-28

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Frontiers of medicine

2024年18卷6期

1087-1099页

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Single-cell transcriptome profiling identifies the activation of type I interferon signaling in ossified posterior longitudinal ligament.

Frontiers of medicine

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Frontiers of medicine

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Single-cell transcriptome profiling identifies the activation of type I interferon signaling in ossified posterior longitudinal ligament.

Frontiers of medicine

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Frontiers of medicine

相关期刊

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