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Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy.

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第一作者: Rishika,Prasad
第一单位: Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.
作者单位: Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX. [1] Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX. [2] Department of Medicine III, Ludwig Maximilian University of Munich University Hospital, Ludwig Maximilian University of Munich, Munich, Germany.;Laboratory for Translational Cancer Immunology, Ludwig Maximilian University of Munich Gene Center, Ludwig Maximilian University of Munich, Munich, Germany.;German Cancer Consortium and Bavarian Center for Cancer Research, Partner Site Munich, Munich, Germany. [3] Department of Hematology, Oncology, and Rheumatology, University Clinic Heidelberg, Heidelberg, Germany. [4] Systems Immunology Department, Weizmann Institute of Science, Rehovot, Israel. [5] Division of Microbiome and Cancer, German Cancer Consortium, Heidelberg, Germany. [6] Department of Blood and Marrow Transplant and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL. [7] Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX. [8] Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX. [9] Department of Stem Cell Transplantation and Cellular Therapy, Roswell Cancer Institute, Buffalo, NY. [10] Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX. [11] Department of Internal Medicine I, University Clinic Tüebingen, Tüebingen, Germany.;M3 Research Institute, Faculty of Medicine, University of Tüebingen, Tüebingen, Germany. [12] Systems Immunology Department, Weizmann Institute of Science, Rehovot, Israel.;Division of Microbiome and Cancer, German Cancer Consortium, Heidelberg, Germany. [13] Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.;Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX. [14] Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX.;Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX. [15]
DOI 10.1182/blood.2024025366
PMID 39441941
发布时间 2026-02-21
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