首页> Journal of advanced research> Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.

Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.

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第一作者： Biao,Kuang

第一单位： State Key Laboratory of Ultrasound in Medicine and Engineering, School of Basic Medical Sciences, Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China.

作者： Biao,Kuang ^[1] ; Nana,Geng ^[1] ; Miao,Yi ^[1] ; Qiqi,Zeng ^[1] ; Mengtian,Fan ^[1] ; Menglin,Xian ^[1] ; Lin,Deng ^[1] ; Cheng,Chen ^[2] ; Yiming,Pan ^[1] ; Liang,Kuang ^[3] ; Fengtao,Luo ^[3] ; Yangli,Xie ^[3] ; Chao,Liu ^[4] ; Zhongliang,Deng ^[5] ; Mao,Nie ^[6] ; Yu,Du ^[7] ; Fengjin,Guo ^[8]

作者单位： State Key Laboratory of Ultrasound in Medicine and Engineering, School of Basic Medical Sciences, Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China. ^[1] Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China. ^[2] Department of Wound Repair and Rehabilitation Medicine, Center of Bone Metabolism and Repair (CBMR), State Key Laboratory of Trauma and Chemical Poisoning, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, China. ^[3] Department of Biomedical Engineering, College of Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Southern University of Science and Technology, Shenzhen, China. ^[4] Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China. ^[5] Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China. Electronic address: 302218@cqmu.edu.cn. ^[6] Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China. Electronic address: duyu@hospital.cqmu.edu.cn. ^[7] State Key Laboratory of Ultrasound in Medicine and Engineering, School of Basic Medical Sciences, Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, Chongqing Medical University, Chongqing, China. Electronic address: guo.fengjin@cqmu.edu.cn. ^[8]

关键词 Cell senescence Fibrosis Osteoarthritis PLGA Panaxatriol UFL1