Establishment of an Integrated Population Pharmacokinetic/Pharmacodynamics Model of Apixaban in Chinese Healthy Population Adjusting for Key Genetic Variants.

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第一作者： Guangyan,Mu

第一单位： Institute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.;Department of Pharmacy, Peking University First Hospital, Beijing, China.

作者： Guangyan,Mu ^[1] ; Ya-Ou,Liu ^[1] ; Qiufen,Xie ^[2] ; Zhiyan,Liu ^[1] ; Hanxu,Zhang ^[3] ; Xianmin,Meng ^[4] ; Jinfang,Song ^[5] ; Zhe,Wang ^[1] ; Shuang,Zhou ^[1] ; Zining,Wang ^[1] ; Kun,Hu ^[1] ; Xia,Zhao ^[2] ; Maoxing,Liao ^[4] ; Jiachun,Bao ^[5] ; Qian,Xiang ^[1] ; Yimin,Cui ^[1]

作者单位： Institute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.;Department of Pharmacy, Peking University First Hospital, Beijing, China. ^[1] Drug Clinical Trial Institution, Peking University First Hospital, Beijing, China. ^[2] Institute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.;Department of Pharmacy, Tianjin Medical University General Hospital, Tianjin, China. ^[3] Department of Pharmacy, Shanghai Public Health Clinical Center, Fudan University, Shanghai, China. ^[4] Department of Pharmacy, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, China. ^[5]

关键词 Apixaban genetic variants healthy volunteers.pharmacodynamics population pharmacokinetics

DOI 10.2174/0113816128306062241007053405

PMID 39449344

发布时间 2024-10-25

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Establishment of an Integrated Population Pharmacokinetic/Pharmacodynamics Model of Apixaban in Chinese Healthy Population Adjusting for Key Genetic Variants.

Current pharmaceutical design

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Current pharmaceutical design

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Establishment of an Integrated Population Pharmacokinetic/Pharmacodynamics Model of Apixaban in Chinese Healthy Population Adjusting for Key Genetic Variants.

Current pharmaceutical design

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Current pharmaceutical design

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