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首页> Phytomedicine : international journal of phytotherapy and phytopharmacology> Fangchinoline suppresses hepatocellular carcinoma by regulating ROS accumulation via the TRIM7/Nrf2 signaling pathway.

Fangchinoline suppresses hepatocellular carcinoma by regulating ROS accumulation via the TRIM7/Nrf2 signaling pathway.

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第一作者： Yange,Liu

第一单位： School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330031, China. Electronic address: liuyange@ncu.edu.cn.

作者： Yange,Liu ^[1] ; Yawen,Wang ^[2] ; Juan,Wang ^[3] ; Xingxing,Wang ^[3] ; Luoting,Chen ^[2] ; Tianyu,Han ^[4] ; Hang,Lian ^[2] ; Mingxi,Gan ^[2] ; Jianbin,Wang ^[5]

作者单位： School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330031, China. Electronic address: liuyange@ncu.edu.cn. ^[1] School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330031, China. ^[2] School of Life Sciences, Liaoning University, Shenyang, Liaoning, 110036, China. ^[3] Jiangxi Institute of Respiratory Disease, The First Affiliated Hospital of Nanchang University, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330006, China. ^[4] School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330031, China. Electronic address: jianbinwang@ncu.edu.cn. ^[5]

关键词 Fangchinoline Hepatocellular carcinoma Nrf2 ROS TRIM7

主题词动物(Animals);癌, 肝细胞(Carcinoma, Hepatocellular);肝肿瘤(Liver Neoplasms);活性氧(Reactive Oxygen Species);苄异喹啉类(Benzylisoquinolines);NF-E2相关因子2(NF-E2-Related Factor 2);信号传导(Signal Transduction);人类(Humans);小鼠(Mice);细胞系, 肿瘤(Cell Line, Tumor);氧化性应激(Oxidative Stress);男(雄)性(Male);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);小鼠, 近交BALB C(Mice, Inbred BALB C)

DOI 10.1016/j.phymed.2024.156143

PMID 39461200

发布时间 2024-11-30

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