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Early inflammation as a footprint of increased mortality risk in infants living with HIV from three African countries.

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作者单位: Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.;Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA. [1] Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.;Department of Systems Medicine, Molecular Medicine, and Applied Biotechnology, University of Rome Tor Vergata, Rome, Italy. [2] Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. [3] Instituto de Investigación Sanitaria Hospital 12 Octubre, Madrid, Spain.;Pediatrics Research Group, Universidad Europea de Madrid, Madrid, Spain. [4] Section of Oncology and Immunology, DiSCOG, University of Padova, Padova, Italy. [5] Instituto de Investigación Sanitaria Hospital 12 Octubre, Madrid, Spain.;Pediatrics Department, Hospital Universitario Infanta Sofía, Infanta Sofia University Hospital and Henares University Hospital Foundation for Biomedical Research and Innovation (FIIB HUIS HHEN), San Sebastián de los Reyes, Madrid, Spain.;Pediatrics Research Group, Universidad Europea de Madrid, Madrid, Spain. [6] Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.;Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, USA. [7] Family Centre for Research With Ubuntu, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. [8] Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.;School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. [9] Fundação Ariel Glaser contra o SIDA Pediátrico, Maputo, Mozambique. [10] University College London, Great Ormond Street Institute for Child Health, Infection, Immunity and Inflammation, London, UK. [11] ISGlobal, Barcelona Institute for Global Health, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain. [12] Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique. [13] University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali. [14] Section of Oncology and Immunology, DiSCOG, University of Padova, Padova, Italy.;Istituto Oncologico Veneto (IOV-IRCCS), Padua, Italy. [15] Universidad Computense de Madrid, Istituto de Investigación Hospital 12 de Octubre, Madrid, Spain. [16] Department for Women's and Children's Health, University of Padova, Via Giustiniani, 3 - 35128, Padua, Italy.;Penta - Child Health Research, Corso Stati Uniti, 4 - 35127, Padua, Italy. [17] Infectious Disease Division, Brigham and Women's Hospital, Boston, MA, USA.;Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. [18] Perinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. [19] Africa Health Research Institute (AHRI), Durban, South Africa. [20] Africa Health Research Institute (AHRI), Durban, South Africa.;Great Ormond Street Institute for Child Health (GOS ICH), University College London (UCL), London, UK. [21] Department of Microbiology and Immunology, Miami Center for AIDS Research, Miller School of Medicine, University of Miami, Miami, USA. [22] Research Unit of Clinical Immunology and Vaccinology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. paolo.palma@opbg.net.;Department of Systems Medicine, Molecular Medicine, and Applied Biotechnology, University of Rome Tor Vergata, Rome, Italy. paolo.palma@opbg.net. [23]
DOI 10.1038/s41598-024-74066-4
PMID 39468166
发布时间 2024-10-31
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