Ganglion cell-derived LysoPS induces retinal neovascularisation by activating the microglial GPR34-PI3K-AKT-NINJ1 axis.

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作者： Lushu,Chen ^[1] ; HuiYing,Zhang ^[1] ; Ying,Zhang ^[1] ; Xiumiao,Li ^[2] ; MeiHuan,Wang ^[2] ; Yaming,Shen ^[2] ; Yuan,Cao ^[3] ; Yong,Xu ^[4] ; Jin,Yao ^[5]

作者单位： The Affiliated Eye Hospital, Nanjing Medical University, 138 Hanzhong Road, Nanjing, 210029, P. R. China.;The Fourth School of Clinical Medicine, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, P. R. China. ^[1] The Affiliated Eye Hospital, Nanjing Medical University, 138 Hanzhong Road, Nanjing, 210029, P. R. China. ^[2] The Fourth School of Clinical Medicine, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, P. R. China. ^[3] The Affiliated Eye Hospital, Nanjing Medical University, 138 Hanzhong Road, Nanjing, 210029, P. R. China. yxu4696@njmu.edu.cn.;The Fourth School of Clinical Medicine, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, P. R. China. yxu4696@njmu.edu.cn. ^[4] The Affiliated Eye Hospital, Nanjing Medical University, 138 Hanzhong Road, Nanjing, 210029, P. R. China. dryaojin@126.com.;The Fourth School of Clinical Medicine, Nanjing Medical University, 140 Hanzhong Road, Nanjing, 210029, P. R. China. dryaojin@126.com. ^[5]

关键词 GPR34 LysoPS Microglial extracellular traps NINJ1 PI3K-AKT Retinal neovascularisation