Crystal structure of a bacterial photoactivated adenylate cyclase determined by serial femtosecond and serial synchrotron crystallography.

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作者： Sofia M,Kapetanaki ^[1] ; Nicolas,Coquelle ^[1] ; David,von Stetten ^[2] ; Martin,Byrdin ^[1] ; Ronald,Rios-Santacruz ^[1] ; Richard,Bean ^[3] ; Johan,Bielecki ^[3] ; Mohamed,Boudjelida ^[1] ; Zsuzsana,Fekete ^[4] ; Geoffrey W,Grime ^[5] ; Huijong,Han ^[3] ; Caitlin,Hatton ^[6] ; Sravya,Kantamneni ^[3] ; Konstantin,Kharitonov ^[3] ; Chan,Kim ^[3] ; Marco,Kloos ^[3] ; Faisal H M,Koua ^[3] ; Iñaki,de Diego Martinez ^[3] ; Diogo,Melo ^[3] ; Lukas,Rane ^[1] ; Adam,Round ^[3] ; Ekaterina,Round ^[3] ; Abhisakh,Sarma ^[3] ; Robin,Schubert ^[3] ; Joachim,Schulz ^[3] ; Marcin,Sikorski ^[3] ; Mohammad,Vakili ^[3] ; Joana,Valerio ^[3] ; Jovana,Vitas ^[1] ; Raphael,de Wijn ^[3] ; Agnieszka,Wrona ^[3] ; Ninon,Zala ^[1] ; Arwen,Pearson ^[6] ; Katerina,Dörner ^[3] ; Giorgio,Schirò ^[1] ; Elspeth F,Garman ^[7] ; András,Lukács ^[4] ; Martin,Weik ^[1]

作者单位： Université Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale, 38044 Grenoble, France. ^[1] European Molecular Biology Laboratory (EMBL), Hamburg Unit c/o DESY, Notkestrasse 85, 22607 Hamburg, Germany. ^[2] European XFEL, Holzkoppel 4, 22869 Schenefeld, Germany. ^[3] Department of Biophysics, Medical School, University of Pecs, Szigeti Street 12, 7624 Pécs, Hungary. ^[4] Surrey Ion Beam Centre, University of Surrey, Guildford GU2 7XH, United Kingdom. ^[5] Institute for Nanostructure and Solid-State Physics, Universität Hamburg, HARBOR, Luruper Chaussee 149, 22761 Hamburg, Germany. ^[6] Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford OX1 3QU, United Kingdom. ^[7]

关键词 AC domain BLUF domain Oscillatoria acuminata XFELs bacterial adenylate cyclase cryo-macromolecular crystallography light-activated enzymes protein structure room-temperature X-ray crystallography serial femtosecond crystallography synchrotrons

主题词结晶学, X线(Crystallography, X-Ray);同步加速器(Synchrotrons);蛋白质构象(Protein Conformation);颤藻属(Oscillatoria);黄素腺嘌呤二核苷酸(Flavin-Adenine Dinucleotide);模型, 分子(Models, Molecular);细菌蛋白质类(Bacterial Proteins)

DOI 10.1107/S2052252524010170

PMID 39470573

发布时间 2024-11-06

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IUCrJ

2024年11卷Pt 6期

991-1006页

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Crystal structure of a bacterial photoactivated adenylate cyclase determined by serial femtosecond and serial synchrotron crystallography.

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Crystal structure of a bacterial photoactivated adenylate cyclase determined by serial femtosecond and serial synchrotron crystallography.

IUCrJ

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