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Machine learning and single-cell RNA sequencing reveal relationship between intratumor CD8<sup>+</sup> T cells and uveal melanoma metastasis.

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第一作者： Shuming,Chen

第一单位： Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.;Hunan Clinical Research Center of Ophthalmic Disease, Changsha, Hunan, 410011, China.

作者： Shuming,Chen ^[1] ; Zichun,Tang ^[1] ; Qiaoqian,Wan ^[2] ; Weidi,Huang ^[1] ; Xie,Li ^[1] ; Xixuan,Huang ^[1] ; Shuyan,Zheng ^[1] ; Caiyang,Lu ^[3] ; Jinzheng,Wu ^[4] ; Zhuo,Li ^[5] ; Xiao,Liu ^[6]

作者单位： Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China.;Hunan Clinical Research Center of Ophthalmic Disease, Changsha, Hunan, 410011, China. ^[1] Department of Anaesthesiology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China. ^[2] Hunan Centre for Drug Review and Adverse Reaction Monitoring, Changsha, Hunan, 410013, China. ^[3] Hunan Provincial Drug Administration, Changsha, Hunan, 410013, China. ^[4] Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China. LiZhuo75@csu.edu.cn.;Hunan Provincial Key Laboratory of Critical Quality Attribute of Cell Therapy Products, Changsha, Hunan, 410013, China. LiZhuo75@csu.edu.cn. ^[5] Department of Ophthalmology, The Second Xiangya Hospital, Central South University, Changsha, 410011, China. Liuxiao8@csu.edu.cn.;Hunan Clinical Research Center of Ophthalmic Disease, Changsha, Hunan, 410011, China. Liuxiao8@csu.edu.cn. ^[6]

关键词 Immune microenvironment Prognostic models Tumour metastasis Uveal melanoma

DOI 10.1186/s12935-024-03539-3

PMID 39478575

发布时间 2024-11-02

基金项目

NO. 2023JJ30770 and 2023JJ60137/the Natural Science Foundation of Hunan Province No. 82000924/the National Natural Science Foundation of China NO. 2024-223/the General Undergraduate Colleges and Universities Teaching Reform Research Project of Hunan Province NO.2024jy067/the Educational Reform Project of Central South University NO. 202207022525/Scientific Research Program Projects of Hunan Provincial Health Commission

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