Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer.

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第一作者： Susrutha,Puthanmadhom Narayanan

第一单位： Division of Oncology, Washington University, St Louis, MO, USA.

作者： Susrutha,Puthanmadhom Narayanan ^[1] ; Abdalla M,Wedn ^[2] ; Osama Shiraz,Shah ^[3] ; Jian,Chen ^[3] ; Daniel D,Brown ^[4] ; Priscilla F,McAuliffe ^[5] ; Steffi,Oesterreich ^[6] ; Adrian V,Lee ^[7]

作者单位： Division of Oncology, Washington University, St Louis, MO, USA. ^[1] Womens Cancer Research Center at UPMC Hillman Cancer Center and Magee Women's Research Institute, Pittsburgh, PA, USA.;Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. ^[2] Womens Cancer Research Center at UPMC Hillman Cancer Center and Magee Women's Research Institute, Pittsburgh, PA, USA. ^[3] Institute for Precision Medicine, University of Pittsburgh, Pittsburgh, PA, USA. ^[4] Division of Surgical Oncology, Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. ^[5] Womens Cancer Research Center at UPMC Hillman Cancer Center and Magee Women's Research Institute, Pittsburgh, PA, USA. oesterreichs@upmc.edu.;Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. oesterreichs@upmc.edu. ^[6] Womens Cancer Research Center at UPMC Hillman Cancer Center and Magee Women's Research Institute, Pittsburgh, PA, USA. leeav@upmc.edu.;Institute for Precision Medicine, University of Pittsburgh, Pittsburgh, PA, USA. leeav@upmc.edu.;Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. leeav@upmc.edu. ^[7]

关键词 CAMP Response Element Binding Protein (CREB)Cyclic AMP (cAMP)Forskolin Invasive carcinoma—No Special Type (NST)Invasive lobular cancer (ILC)Protein Kinase A (PKA)