Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing.

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作者： Andrew M,Overmiller ^[1] ; Akihiko,Uchiyama ^[1] ; Emma D,Hope ^[1] ; Subhashree,Nayak ^[1] ; Christopher G,O'Neill ^[1] ; Kowser,Hasneen ^[1] ; Yi-Wen,Chen ^[2] ; Faiza,Naz ^[3] ; Stefania,Dell'Orso ^[3] ; Stephen R,Brooks ^[4] ; Kan,Jiang ^[4] ; Maria I,Morasso ^[1]

作者单位： Laboratory of Skin Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland, USA. ^[1] Department of Genomics and Precision Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.;Center for Genetic Medicine Research, Children's National Hospital, Washington, DC, USA. ^[2] Genomic Technology Section and. ^[3] Biodata Mining and Discovery Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland, USA. ^[4]

关键词 Bioinformatics Dermatology Mouse models Skin

主题词动物(Animals);角蛋白细胞(Keratinocytes);伤口愈合(Wound Healing);小鼠(Mice);成对盒转录因子类(Paired Box Transcription Factors);细胞增殖(Cell Proliferation);细胞分化(Cell Differentiation);细胞运动(Cell Movement);表皮(Epidermis);口腔黏膜(Mouth Mucosa);皮肤(Skin)

DOI 10.1172/jci.insight.182844

PMID 39480496

发布时间 2025-01-04

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2024年9卷24期

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Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing.

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Reprogramming of epidermal keratinocytes by PITX1 transforms the cutaneous cellular landscape and promotes wound healing.

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