TMED4 facilitates regulatory T cell suppressive function via ROS homeostasis in tumor and autoimmune mouse models.
第一作者:
Zhenyan,Jiang
第一单位:
Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital.;Hongqiao International Institute of Medicine, Shanghai Tongren Hospital.;Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, and.;Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China.
作者:
医学主题词
动物(Animals);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);小鼠(Mice);活性氧(Reactive Oxygen Species);内环境稳定(Homeostasis);小鼠, 基因敲除(Mice, Knockout);NF-E2相关因子2(NF-E2-Related Factor 2);内切核糖核酸酶类(Endoribonucleases);膜蛋白质类(Membrane Proteins);叉头转录因子类(Forkhead Transcription Factors);疾病模型, 动物(Disease Models, Animal)
DOI
10.1172/JCI179874
PMID
39480507
发布时间
2025-01-11
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