换一批
换一批Perivascular space enlargement accelerates in ageing and Alzheimer's disease pathology: evidence from a three-year longitudinal multicentre study.
作者：
Inga,Menze [1]
;
Jose,Bernal [2]
;
Pinar,Kaya [3]
;
Çağla,Aki [3]
;
Malte,Pfister [4]
;
Jonas,Geisendörfer [4]
;
Renat,Yakupov [5]
;
Roberto Duarte,Coello [6]
;
Maria D C,Valdés-Hernández [6]
;
Michael T,Heneka [7]
;
Frederic,Brosseron [8]
;
Matthias C,Schmid [9]
;
Wenzel,Glanz [5]
;
Enise I,Incesoy [10]
;
Michaela,Butryn [5]
;
Ayda,Rostamzadeh [11]
;
Dix,Meiberth [12]
;
Oliver,Peters [13]
;
Lukas,Preis [14]
;
Dominik,Lammerding [14]
;
Daria,Gref [14]
;
Josef,Priller [15]
;
Eike J,Spruth [16]
;
Slawek,Altenstein [16]
;
Andrea,Lohse [17]
;
Stefan,Hetzer [18]
;
Anja,Schneider [19]
;
Klaus,Fliessbach [19]
;
Okka,Kimmich [8]
;
Ina R,Vogt [8]
;
Jens,Wiltfang [20]
;
Claudia,Bartels [21]
;
Björn H,Schott [22]
;
Niels,Hansen [21]
;
Peter,Dechent [23]
;
Katharina,Buerger [24]
;
Daniel,Janowitz [25]
;
Robert,Perneczky [26]
;
Boris-Stephan,Rauchmann [27]
;
Stefan,Teipel [28]
;
Ingo,Kilimann [28]
;
Doreen,Goerss [28]
;
Christoph,Laske [29]
;
Matthias H,Munk [30]
;
Carolin,Sanzenbacher [31]
;
Petra,Hinderer [31]
;
Klaus,Scheffler [32]
;
Annika,Spottke [33]
;
Nina,Roy-Kluth [8]
;
Falk,Lüsebrink [34]
;
Katja,Neumann [4]
;
Joanna,Wardlaw [6]
;
Frank,Jessen [35]
;
Stefanie,Schreiber [3]
;
Emrah,Düzel [5]
;
Gabriel,Ziegler [5]
作者单位：
German Centre for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, Magdeburg, 39120, Germany. inga.menze@dzne.de.;Institute of Cognitive Neurology and Dementia Research, Otto-Von-Guericke University Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany. inga.menze@dzne.de.
[1]
German Centre for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, Magdeburg, 39120, Germany.;Institute of Cognitive Neurology and Dementia Research, Otto-Von-Guericke University Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany.;Centre for Clinical Brain Sciences, The University of Edinburgh, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.;UK Dementia Research Institute Centre at the University of Edinburgh, Edinburgh Bioquarter, 49 Little France Crescent, Edinburgh Bioquarter, Edinburgh, EH16 4SB, UK.
[2]
German Centre for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, Magdeburg, 39120, Germany.;Department of Neurology, University Hospital Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany.
[3]
Department of Neurology, University Hospital Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany.
[4]
German Centre for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, Magdeburg, 39120, Germany.;Institute of Cognitive Neurology and Dementia Research, Otto-Von-Guericke University Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany.
[5]
Centre for Clinical Brain Sciences, The University of Edinburgh, 49 Little France Crescent, Edinburgh, EH16 4SB, UK.;UK Dementia Research Institute Centre at the University of Edinburgh, Edinburgh Bioquarter, 49 Little France Crescent, Edinburgh Bioquarter, Edinburgh, EH16 4SB, UK.
[6]
Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Belvaux, 6 Avenue du Swing 4367 , Esch-Belval, Luxembourg.
[7]
German Centre for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn, 53127, Germany.
[8]
German Centre for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn, 53127, Germany.;Institute for Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Venusberg-Campus 1, Bonn, 53127, Germany.
[9]
German Centre for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, Magdeburg, 39120, Germany.;Institute of Cognitive Neurology and Dementia Research, Otto-Von-Guericke University Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany.;Department of Psychiatry and Psychotherapy, University Hospital Magdeburg, Leipziger Str. 44, Magdeburg, 39120, Germany.
[10]
Department of Psychiatry, Medical Faculty, University of Cologne, Kerpener Strasse 62, Cologne, 50924, Germany.
[11]
German Centre for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn, 53127, Germany.;Department of Psychiatry, Medical Faculty, University of Cologne, Kerpener Strasse 62, Cologne, 50924, Germany.
[12]
German Centre for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin, 10117, Germany.;Institute of Psychiatry and Psychotherapy, Freie Universität Berlin and Humboldt-Universität zu Berlin, Hindenburgdamm 30, Berlin, 12203, Germany.
[13]
Institute of Psychiatry and Psychotherapy, Freie Universität Berlin and Humboldt-Universität zu Berlin, Hindenburgdamm 30, Berlin, 12203, Germany.
[14]
UK Dementia Research Institute Centre at the University of Edinburgh, Edinburgh Bioquarter, 49 Little France Crescent, Edinburgh Bioquarter, Edinburgh, EH16 4SB, UK.;German Centre for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin, 10117, Germany.;Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, Berlin, 10117, Germany.;School of Medicine, Department of Psychiatry and Psychotherapy, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany.
[15]
German Centre for Neurodegenerative Diseases (DZNE), Charitéplatz 1, Berlin, 10117, Germany.;Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, Berlin, 10117, Germany.
[16]
Department of Psychiatry and Psychotherapy, Charité, Charitéplatz 1, Berlin, 10117, Germany.
[17]
Berlin Center for Advanced Neuroimaging, Charité, Charitéplatz 1, Berlin, 10117, Germany.
[18]
German Centre for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn, 53127, Germany.;Department of Neurodegenerative Disease and Geriatric Psychiatry/Psychiatry, University of Bonn Medical Center, Venusberg-Campus 1, Bonn, 53127, Germany.
[19]
German Centre for Neurodegenerative Diseases (DZNE), Von-Siebold-Str. 3a, 37075, Goettingen, Germany.;Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Von-Siebold-Str. 5, Goettingen, 37075, Germany.;Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Campus Universitário de Santiago, Aveiro, 3810-193, Portugal.
[20]
Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Von-Siebold-Str. 5, Goettingen, 37075, Germany.
[21]
German Centre for Neurodegenerative Diseases (DZNE), Von-Siebold-Str. 3a, 37075, Goettingen, Germany.;Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Von-Siebold-Str. 5, Goettingen, 37075, Germany.;Leibniz Institute for Neurobiology, Brenneckestraße 6, Magdeburg, 39118, Germany.
[22]
Department of Cognitive Neurology, MR-Research in Neurosciences, Georg-August-University Goettingen, Robert-Koch-Straße 40, Göttingen, 37075, Germany.
[23]
German Centre for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Strasse 17, Munich, 81377, Germany.;Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Feodor-Lynen-Strasse 17, Munich, 81377, Germany.
[24]
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Feodor-Lynen-Strasse 17, Munich, 81377, Germany.
[25]
German Centre for Neurodegenerative Diseases (DZNE), Feodor-Lynen-Strasse 17, Munich, 81377, Germany.;Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nußbaumstraße 7, Munich, München, 80336 , Germany.;Munich Cluster for Systems Neurology (SyNergy), Feodor-Lynen-Str. 17, Munich, 81377, Germany.;Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, Charing Cross Hospital, St Dunstan's Road, London, W6 8RP, UK.
[26]
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nußbaumstraße 7, Munich, München, 80336 , Germany.;Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, 385a Glossop Rd, Sheffield, Broomhall, Sheffield, S10 2HQ, UK.;Department of Neuroradiology, University Hospital LMU, Marchioninistr. 15, Munich, 81377, Germany.
[27]
German Centre for Neurodegenerative Diseases (DZNE), Gehlsheimer Straße 20, Rostock, 18147, Germany.;Department of Psychosomatic Medicine, Rostock University Medical Center, Gehlsheimer Straße 20, Rostock, 18147, Germany.
[28]
German Centre for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 23, Tübingen, 72076, Germany.;Section for Dementia Research, Hertie Institute for Clinical Brain Research and Department of Psychiatry and Psychotherapy, University of Tübingen, Osianderstraße 24, Tübingen, 72076, Germany.
[29]
German Centre for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 23, Tübingen, 72076, Germany.;Department of Psychiatry and Psychotherapy, University of Tübingen, Osianderstraße 24, Tübingen, 72076 , Germany.
[30]
German Centre for Neurodegenerative Diseases (DZNE), Otfried-Müller-Straße 23, Tübingen, 72076, Germany.
[31]
Department for Biomedical Magnetic Resonance, University of Tübingen, Otfried-Müller-Straße 51, Tübingen, 72076, Germany.
[32]
German Centre for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn, 53127, Germany.;Department of Neurology, University of Bonn, Venusberg-Campus 1, Bonn, 53127, Germany.
[33]
German Centre for Neurodegenerative Diseases (DZNE), Leipziger Str. 44, Magdeburg, 39120, Germany.
[34]
German Centre for Neurodegenerative Diseases (DZNE), Venusberg-Campus 1, Bonn, 53127, Germany.;Department of Psychiatry, Medical Faculty, University of Cologne, Kerpener Strasse 62, Cologne, 50924, Germany.;Excellence Cluster On Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Straße 26, Cologne, 50931, Germany.
[35]
主题词
人类(Humans);女(雌)性(Female);男(雄)性(Male);老年人(Aged);阿尔茨海默病(Alzheimer Disease);纵向研究(Longitudinal Studies);衰老(Aging);磁共振成像(Magnetic Resonance Imaging);脑(Brain);老年人, 80以上(Aged, 80 and over);横断面研究(Cross-Sectional Studies);中年人(Middle Aged)
DOI
10.1186/s13195-024-01603-8
PMID
39482759
发布时间
2024-11-20
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Alzheimer's research & therapy
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