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An integrated view of the structure and function of the human 4D nucleome.

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第一作者: 4D Nucleome Consortium
第一单位: Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.;Howard Hughes Medical Institute, Chevy Chase, MD, USA.
作者: 4D Nucleome Consortium [1] ; Job,Dekker [2] ; Betul Akgol,Oksuz [3] ; Yang,Zhang [4] ; Ye,Wang [5] ; Miriam K,Minsk [6] ; Shuzhen,Kuang [2] ; Liyan,Yang [2] ; Johan H,Gibcus [7] ; Nils,Krietenstein [8] ; Oliver J,Rando [9] ; Jie,Xu [10] ; Derek H,Janssens [11] ; Steven,Henikoff [12] ; Alexander,Kukalev [12] ; Andréa,Willemin [12] ; Warren,Winick-Ng [12] ; Rieke,Kempfer [12] ; Ana,Pombo [13] ; Miao,Yu [14] ; Pradeep,Kumar [14] ; Liguo,Zhang [14] ; Andrew S,Belmont [15] ; Takayo,Sasaki [16] ; Tom,van Schaik [17] ; Laura,Brueckner [16] ; Daan,Peric-Hupkes [16] ; Bas,van Steensel [9] ; Ping,Wang [18] ; Haoxi,Chai [19] ; Minji,Kim [18] ; Yijun,Ruan [20] ; Ran,Zhang [21] ; Sofia A,Quinodoz [22] ; Prashant,Bhat [23] ; Mitchell,Guttman [24] ; Wenxin,Zhao [24] ; Shu,Chien [24] ; Yuan,Liu [2] ; Sergey V,Venev [25] ; Dariusz,Plewczynski [12] ; Ibai Irastorza,Azcarate [12] ; Dominik,Szabó [12] ; Christoph J,Thieme [26] ; Teresa,Szczepińska [27] ; Mateusz,Chiliński [27] ; Kaustav,Sengupta [28] ; Mattia,Conte [28] ; Andrea,Esposito [28] ; Alex,Abraham [3] ; Ruochi,Zhang [3] ; Yuchuan,Wang [29] ; Xingzhao,Wen [24] ; Qiuyang,Wu [3] ; Yang,Yang [19] ; Jie,Liu [4] ; Lorenzo,Boninsegna [4] ; Asli,Yildirim [4] ; Yuxiang,Zhan [28] ; Andrea Maria,Chiariello [28] ; Simona,Bianco [30] ; Lindsay,Lee [30] ; Ming,Hu [31] ; Yun,Li [5] ; R Jordan,Barnett [5] ; Ashley L,Cook [5] ; Daniel J,Emerson [32] ; Claire,Marchal [15] ; Peiyao,Zhao [33] ; Peter,Park [33] ; Burak H,Alver [33] ; Andrew,Schroeder [33] ; Rahi,Navelkar [33] ; Clara,Bakker [33] ; William,Ronchetti [33] ; Shannon,Ehmsen [33] ; Alexander,Veit [33] ; Nils,Gehlenborg [34] ; Ting,Wang [34] ; Daofeng,Li [35] ; Xiaotao,Wang [28] ; Mario,Nicodemi [36] ; Bing,Ren [24] ; Sheng,Zhong [5] ; Jennifer E,Phillips-Cremins [15] ; David M,Gilbert [6] ; Katherine S,Pollard [4] ; Frank,Alber [3] ; Jian,Ma [20] ; William S,Noble [37] ; Feng,Yue
作者单位: Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.;Howard Hughes Medical Institute, Chevy Chase, MD, USA. [1] Department of Systems Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA. [2] Ray and Stephanie Lane Computational Biology Department, School of Computer Science, Carnegie Mellon University. [3] Department of Microbiology, Immunology, and Molecular Genetics; Institute for Quantitative and Computational Biosciences, University of California Los Angeles, Los Angeles, CA, USA. [4] Department of Genetics, Department of Bioengineering, Epigenetics Institute, University of Pennsylvania, Philadelphia, PA, USA. [5] Gladstone Institutes, San Francisco, CA 94158. [6] Novo Nordisk Foundation Center for Protein Research, University of Copenhagen. [7] Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA. [8] Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, Illinois, USA. [9] Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.;Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, USA. [10] Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.;Howard Hughes Medical Institute, Chevy Chase, MD, USA. [11] Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Epigenetic Regulation and Chromatin Architecture Group, 10115 Berlin, Germany. [12] University of California, San Diego School of Medicine, Department of Cellular and Molecular Medicine, La Jolla, CA, USA.;State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China. [13] Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. [14] San Diego Biomedical Research Institute, San Diego, CA, USA. [15] Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands.;Oncode Institute, the Netherlands. [16] Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, the Netherlands. [17] Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang Province, 310058, P.R. China. [18] Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA. [19] Department of Genome Sciences, University of Washington, Seattle, WA 98195. [20] Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.;Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA. [21] Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.;David Geffen School of Medicine at UCLA, Los Angeles, USA. [22] Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. [23] Shu Chien-Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, CA, USA. [24] Laboratory of Bioinformatics and Computational Genomics, Faculty of Mathematics and Information Science, Warsaw University of Technology ul. Koszykowa 75, 00-662 Warsaw, Poland.;Laboratory of Functional and Structural Genomics, Centre of New Technologies, University of Warsaw, Banacha 2c Street, 02-097 Warsaw, Poland. [25] Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Epigenetic Regulation and Chromatin Architecture Group, 10115 Berlin, Germany.;Centre for Advanced Materials and Technologies CEZAMAT, Warsaw University of Technology, Poleczki 19, 02-822 Warsaw, Poland.;Laboratory of Functional and Structural Genomics, Centre of New Technologies, University of Warsaw, Banacha 2c Street, 02-097 Warsaw, Poland. [26] Laboratory of Bioinformatics and Computational Genomics, Faculty of Mathematics and Information Science, Warsaw University of Technology ul. Koszykowa 75, 00-662 Warsaw, Poland. [27] Department of Physics, University of Naples "Federico II", Naples, Italy; INFN, Naples, Italy. [28] Program in Bioinformatics and Systems Biology, University of California San Diego, La Jolla, CA, USA. [29] Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA. [30] Department of Biostatistics, Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA. [31] In silichrom Ltd, Newbury, UK. [32] Department of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115. [33] Department of Genetics, Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO, USA. [34] Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, Illinois, USA.;Obstetrics and Gynecology Hospital, Institute of Reproduction and Development, Fudan University, Shanghai, China. [35] University of California, San Diego School of Medicine, Department of Cellular and Molecular Medicine, La Jolla, CA, USA. [36] Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, Illinois, USA.;Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, Illinois, USA. [37]
DOI 10.1101/2024.09.17.613111
PMID 39484446
发布时间 2026-01-13
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