Nanoconjugate Carrying pH-Responsive Transferrin Receptor-Targeted Hesperetin Triggers Triple-Negative Breast Cancer Cell Death through Oxidative Attack and Assemblage of Pro-Apoptotic Proteins.

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作者： Dibyendu,Giri ^[1] ; Surya Kanta,Dey ^[2] ; Sounik,Manna ^[2] ; Angsuman,Das Chaudhuri ^[2] ; Rumi,Mahata ^[2] ; Ananya,Pradhan ^[2] ; Tamanna,Roy ^[2] ; Kuladip,Jana ^[3] ; Subhasis,Das ^[4] ; Sumita,Roy ^[5] ; Sujata,Maiti Choudhury ^[2]

作者单位： Biochemistry, Molecular Endocrinology and Reproductive Physiology Laboratory, Department of Human Physiology, Vidyasagar University, Midnapore, West Bengal, India, 721102.;Department of Physiology, Ghatal Rabindra Satabarsiki Mahavidyalaya, Ghatal, Paschim Medinipur, West Bengal, India, 721212. ^[1] Biochemistry, Molecular Endocrinology and Reproductive Physiology Laboratory, Department of Human Physiology, Vidyasagar University, Midnapore, West Bengal, India, 721102. ^[2] Division of Molecular Medicine, Bose Institute, P1/12 CIT scheme VIIM, Kolkata, West Bengal, India, 700054. ^[3] Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, United States. ^[4] Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore, West Bengal, India, 721102. ^[5]

关键词 Apoptosis Hesperetin Oxidative assault Transferrin Triple-negative breast cancer Tumor cell regression

主题词橙皮苷(Hesperidin);人类(Humans);抗肿瘤药(Antineoplastic Agents);动物(Animals);氢离子浓度(Hydrogen-Ion Concentration);细胞凋亡(Apoptosis);纳米共轭体(Nanoconjugates);受体, 转铁蛋白(Receptors, Transferrin);小鼠(Mice);女(雌)性(Female);生物相容性材料(Biocompatible Materials);细胞系, 肿瘤(Cell Line, Tumor);材料试验(Materials Testing);氧化性应激(Oxidative Stress);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);粒子大小(Particle Size);细胞增殖(Cell Proliferation);细胞存活(Cell Survival)

DOI 10.1021/acsabm.4c01131

PMID 39504304

发布时间 2024-11-18

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ACS applied bio materials

2024年7卷11期

7556-7573页

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Nanoconjugate Carrying pH-Responsive Transferrin Receptor-Targeted Hesperetin Triggers Triple-Negative Breast Cancer Cell Death through Oxidative Attack and Assemblage of Pro-Apoptotic Proteins.

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Nanoconjugate Carrying pH-Responsive Transferrin Receptor-Targeted Hesperetin Triggers Triple-Negative Breast Cancer Cell Death through Oxidative Attack and Assemblage of Pro-Apoptotic Proteins.

ACS applied bio materials

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ACS applied bio materials

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