Effect of lubricants type and particle size on the rheological properties and aerosolization behavior of dry powder inhalers.

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第一作者： Jiayi,Li

第一单位： School of Pharmacy, Shenyang Key Laboratory of Intelligent Mucosal Drug Delivery Systems, Shenyang Pharmaceutical University, Shenyang 110016, China.

作者： Jiayi,Li ^[1] ; Xianhong,He ^[1] ; Ying,Sun ^[1] ; Ruxiao,Song ^[1] ; Xuhong,Ren ^[2] ; Xin,Zhang ^[3] ; Jian,Guan ^[3] ; Shirui,Mao ^[4]

作者单位： School of Pharmacy, Shenyang Key Laboratory of Intelligent Mucosal Drug Delivery Systems, Shenyang Pharmaceutical University, Shenyang 110016, China. ^[1] School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: renxuhong2003@163.com. ^[2] School of Pharmacy, Shenyang Key Laboratory of Intelligent Mucosal Drug Delivery Systems, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, China. ^[3] School of Pharmacy, Shenyang Key Laboratory of Intelligent Mucosal Drug Delivery Systems, Shenyang Pharmaceutical University, Shenyang 110016, China; Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, China. Electronic address: maoshirui@syphu.edu.cn. ^[4]

关键词 Dry powder inhaler (DPI)In-vitro lung deposition Lubricant Powder properties