Multiphysics simulations reveal haemodynamic impacts of patient-derived fibrosis-related changes in left atrial tissue mechanics.

导出 OA

翻译打印收藏纠错

第一作者： Alejandro,Gonzalo

第一单位： Department of Mechanical Engineering, University of Washington, Seattle, WA, USA.

作者： Alejandro,Gonzalo ^[1] ; Christoph M,Augustin ^[2] ; Savannah F,Bifulco ^[3] ; Åshild,Telle ^[3] ; Yaacoub,Chahine ^[4] ; Ahmad,Kassar ^[4] ; Manuel,Guerrero-Hurtado ^[5] ; Eduardo,Durán ^[6] ; Pablo,Martínez-Legazpi ^[7] ; Oscar,Flores ^[5] ; Javier,Bermejo ^[8] ; Gernot,Plank ^[9] ; Nazem,Akoum ^[4] ; Patrick M,Boyle ^[3] ; Juan C,Del Alamo ^[10]

作者单位： Department of Mechanical Engineering, University of Washington, Seattle, WA, USA. ^[1] Gottfried Schatz Research Center, Division of Biophysics, Medical University of Graz, Graz, Austria. ^[2] Department of Bioengineering, University of Washington, Seattle, WA, USA. ^[3] School of Cardiology, University of Washington, Seattle, WA, USA. ^[4] Department of Aerospace and Biomedical Engineering, Universidad Carlos III de Madrid, Leganés, Spain. ^[5] Dept. Ing. Mecánica, Térmica y de Fluidos, Universidad de Málaga, Málaga, Spain. ^[6] Department of Mathematical and Fluid Physics, UNED, Madrid, Spain. ^[7] Hospital General Universitario Gregorio Marañón, Madrid, Spain.;Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.;Medical School, Complutense University of Madrid, Madrid, Spain. ^[8] Gottfried Schatz Research Center, Division of Biophysics, Medical University of Graz, Graz, Austria.;BioTechMed-Graz, Graz, Austria. ^[9] Department of Mechanical Engineering, University of Washington, Seattle, WA, USA.;Center for Cardiovascular Biology, University of Washington, Seattle, WA, USA.;Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA. ^[10]

关键词 computational fluid dynamics electromechanics emptying fraction fibrosis haemodynamics left atrium multiphysics thrombosis