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CSTF2 Supports Hypoxia Tolerance in Hepatocellular Carcinoma by Enabling m6A Modification Evasion of PGK1 to Enhance Glycolysis.

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作者: Qiangnu,Zhang [1] ; Yusen,Zhang [2] ; Chuli,Fu [3] ; Xiaoyan,He [4] ; Zuotian,Huang [5] ; Geyan,Wu [6] ; Teng,Wei [7] ; Wen,Jin [8] ; Lesen,Yan [2] ; Meilong,Wu [2] ; Gongze,Peng [2] ; LinLan,Fan [9] ; Mingyue,Li [2] ; Yuehua,Guo [2] ; Jiangang,Bi [2] ; Yu,Bai [2] ; Stephanie,Roessler [10] ; Guang-Rong,Yan [6] ; Liping,Liu [2]
作者单位: Division of Hepatobiliary and Pancreas Surgery, Department of General Surgery, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China.;Biomedicine Research Center, Guangdong Provincial Key Laboratory of Major Obstetric Disease, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. [1] Division of Hepatobiliary and Pancreas Surgery, Department of General Surgery, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China. [2] Department of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China. [3] Department of Pathology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China. [4] Department of Hepatobiliary and Pancreatic Tumor Center, Chongqing University Cancer Hospital, Chongqing, China. [5] Biomedicine Research Center, Guangdong Provincial Key Laboratory of Major Obstetric Disease, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. [6] Cytotherapy Laboratory, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China. [7] Department of Neurology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, China. [8] Experimental and teaching Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China. [9] Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany. [10]
DOI 10.1158/0008-5472.CAN-24-2283
PMID 39514400
发布时间 2025-02-01
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