Hesperidin alleviated dendritic spines through inhibiting ferritinophagy via HERC2-NCOA4 ubiquitination in CUMS mice.

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第一作者： Mingjia,Zhang

第一单位： Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou, China; Zhejiang Engineering Research Center for "Preventive Treatment" Smart Health of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou, China; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China; Southern Medicine University, Sch Tradit Chinese Med, Guangzhou, China.

作者： Mingjia,Zhang ^[1] ; Yixuan,Cui ^[2] ; Ruiting,Jia ^[3] ; Ziling,Cai ^[3] ; Yineng,Shen ^[3] ; Wumin,Yu ^[3] ; Zixin,Pang ^[4] ; Shuning,Ding ^[3] ; Xing,Gao ^[4] ; Yike,Huang ^[4] ; Maolin,Song ^[2] ; Yahui,Lou ^[3] ; Fa,Ye ^[5] ; Haiqing,Ao ^[6] ; Aisong,Zhu ^[7]

作者单位： Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou, China; Zhejiang Engineering Research Center for "Preventive Treatment" Smart Health of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou, China; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China; Southern Medicine University, Sch Tradit Chinese Med, Guangzhou, China. ^[1] The First Clinical Medical College, Guangzhou University of Chinese Medicine, China. ^[2] Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou, China; Zhejiang Engineering Research Center for "Preventive Treatment" Smart Health of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou, China; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China. ^[3] Zhejiang Engineering Research Center for "Preventive Treatment" Smart Health of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou, China. ^[4] Sleep Medicine Center, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, China. Electronic address: yefaa0311@126.com. ^[5] School of Public Health and Management, Guangzhou University of Chinese Medicin, China. Electronic address: aohaiqing@gzucm.edu.cn. ^[6] Zhejiang Key Laboratory of Blood-Stasis-Toxin Syndrome, Zhejiang Chinese Medical University, Hangzhou, China; Zhejiang Engineering Research Center for "Preventive Treatment" Smart Health of Traditional Chinese Medicine, Zhejiang Chinese Medical University, Hangzhou, China; College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China. Electronic address: liaoningzhongyi@hotmail.com. ^[7]

关键词 CUMS Ferritinophagy HERC2-NCOA4 Hesperidin

主题词动物(Animals);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠(Mice);泛素化(Ubiquitination);男(雄)性(Male);橙皮苷(Hesperidin);树突棘(Dendritic Spines);应激, 心理学(Stress, Psychological);铁蛋白质类(Ferritins);抑郁(Depression);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);疾病模型, 动物(Disease Models, Animal);自噬(Autophagy);氟西汀(Fluoxetine);鸟嘌呤核苷酸交换因子类(Guanine Nucleotide Exchange Factors)

DOI 10.1016/j.phymed.2024.156132

PMID 39522250

发布时间 2024-11-30

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Hesperidin alleviated dendritic spines through inhibiting ferritinophagy via HERC2-NCOA4 ubiquitination in CUMS mice.

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Hesperidin alleviated dendritic spines through inhibiting ferritinophagy via HERC2-NCOA4 ubiquitination in CUMS mice.

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