Knockdown of hepatic mitochondrial calcium uniporter mitigates MASH and fibrosis in mice.

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第一作者： Shuyu,Li

第一单位： Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

作者： Shuyu,Li ^[1] ; Fangyuan,Chen ^[1] ; Min,Liu ^[2] ; Yajun,Zhang ^[2] ; Jingjing,Xu ^[3] ; Xi,Li ^[4] ; Zhiyin,Shang ^[2] ; Shaoping,Huang ^[2] ; Shu,Song ^[5] ; Chuantao,Tu ^[6]

作者单位： Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. ^[1] Department of Gastroenterology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. ^[2] Department of Pathology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. ^[3] Department of Geriatrics, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. ^[4] Department of Pathology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. songshu@shaphc.org. ^[5] Department of Gastroenterology, Shanghai Public Health Clinical Center, Fudan University, Shanghai, 201508, China. tuchuantao@shaphc.org. ^[6]

关键词 Liver fibrosis MCU Mitochondrial dysfunction Oxidative stress Steatohepatitis

DOI 10.1186/s13578-024-01315-4

PMID 39523398

发布时间 2024-11-16

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