Autoimmunity, a relevant exclusion criterion in the development of mRNA-based compounds: A systematic review of clinical trials registries.

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第一作者： Larisa,Pinte

第一单位： Clinical Department 5, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Departments of Internal Medicine and Rheumatology, Colentina Clinical Hospital, Bucharest, Romania; Department for Evidence-based Medicine and Evaluation, University for Continuing Education Krems, Austria.

作者： Larisa,Pinte ^[1] ; Alina,Dima ^[2] ; Anamaria,Draghici ^[3] ; Maria,Caraghiulea ^[4] ; Ioana Andreea,Zamfir-Gradinaru ^[5] ; Cristian,Baicus ^[6]

作者单位： Clinical Department 5, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Departments of Internal Medicine and Rheumatology, Colentina Clinical Hospital, Bucharest, Romania; Department for Evidence-based Medicine and Evaluation, University for Continuing Education Krems, Austria. ^[1] Clinical Department 5, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Departments of Internal Medicine and Rheumatology, Colentina Clinical Hospital, Bucharest, Romania. Electronic address: alina_dima@outlook.com. ^[2] Clinical Department 5, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Department of Internal Medicine, Academician Stefan Milcu Ambulatory Diagnostic and Treatment Medical Center, Bucharest, Romania. ^[3] Department of Allergology and Clinical Immunology, Nicolae Malaxa Clinical Hospital, Bucharest, Romania. ^[4] Departments of Internal Medicine and Rheumatology, Colentina Clinical Hospital, Bucharest, Romania. ^[5] Clinical Department 5, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Departments of Internal Medicine and Rheumatology, Colentina Clinical Hospital, Bucharest, Romania. ^[6]

关键词 Autoimmune disease BNT162b2 mRNA (Pfizer- BioNTech)COVID-19 Corticosteroid Immunosuppressive treatment Messenger RNA, mRNA Non-replicating RNA Self-amplifying RNA mRNA vaccine mRNA-1273 (Moderna)

主题词人类(Humans);自身免疫疾病(Autoimmune Diseases);RNA, 信使(RNA, Messenger);登记(Registries);临床试验(主题)(Clinical Trials as Topic);自身免疫(Autoimmunity);免疫抑制剂(Immunosuppressive Agents)

DOI 10.1016/j.autrev.2024.103670

PMID 39527992

发布时间 2024-12-04

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