Nuclear factor kappa-B cell (NF-κB), interferon regulatory Factor, and glucocorticoid receptor pathway activation in major depressive Disorder: The role of cytomegalovirus infection.

导出 OA

翻译打印收藏纠错

作者： Jonathan,Savitz ^[1] ; Brett A,McKinney ^[2] ; Timothy B,Meier ^[3] ; Haixia,Zheng ^[4] ; Bart N,Ford ^[5] ; Robert H,Yolken ^[6] ; T Kent,Teague ^[7] ; Steve W,Cole ^[8]

作者单位： Laureate Institute for Brain Research, Tulsa OK, USA; Oxley College of Health and Natural Sciences, The University of Tulsa, Tulsa OK, USA. Electronic address: jsavitz@laureateinstitute.org. ^[1] Department of Mathematics and Computer Science, The University of Tulsa, Tulsa, OK, USA. ^[2] Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI USA. ^[3] Laureate Institute for Brain Research, Tulsa OK, USA; Oxley College of Health and Natural Sciences, The University of Tulsa, Tulsa OK, USA. ^[4] Department of Pharmacology and Physiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA. ^[5] Stanley Division of Developmental Neurovirology, Johns Hopkins School of Medicine, Baltimore, MD, USA. ^[6] Department of Surgery, University of Oklahoma School of Community Medicine, Tulsa, OK, USA; Department of Psychiatry, University of Oklahoma School of Community Medicine, Tulsa, OK, USA; Department of Biochemistry and Microbiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA. ^[7] University of California, Los Angeles, Cousins Center for Psychoneuroimmunology, Los Angeles, CA, USA; University of California, Los Angeles, David Geffen School of Medicine, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, USA. ^[8]

关键词 Cytomegalovirus Glucocorticoid Infection Inflammation Interferon Major Depressive Disorder Nuclear Factor Kappa-B Cell RNAseq Transcriptomics