Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs.

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第一作者： Popat,Mohite

第一单位： AETs St. John Institute of Pharmacy and Research, Manor Road, Palghar, Maharashtra, India.

作者： Popat,Mohite ^[1] ; Shruti,Sule ^[2] ; Anil,Pawar ^[2] ; Hanan M,Alharbi ^[3] ; Swastika,Maitra ^[4] ; Vetriselvan,Subramaniyan ^[5] ; Vinoth,Kumarasamy ^[6] ; Daniel Ejim,Uti ^[7] ; Celestine O,Ogbu ^[8] ; Simon Inedu,Oodo ^[8] ; Ajoy,Kumer ^[9] ; Ayodeji Oluwafemi,Idowu ^[10] ; Okechukwu N N,Okoye ^[11]

作者单位： AETs St. John Institute of Pharmacy and Research, Manor Road, Palghar, Maharashtra, India. ^[1] MES's College of Pharmacy, Sonai, Tal- Newasa, Ahmednagar, Maharashtra, India. ^[2] Department of Pharmaceutical Sciences, College of Pharmacy, Umm Al-Qura University, Makkah, 21955, Saudi Arabia. ^[3] Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, India. ^[4] Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY, 10032, USA. ^[5] Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Cheras, Kuala Lumpur, 56000, Malaysia. ^[6] Department of Research Publications, Kampala International University, Main Campus, P. O. Box 20000, Kampala, Uganda. daniel.ejimuti@kiu.ac.ug.;Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, Federal University of Health Sciences, Otukpo, Benue State, Nigeria. daniel.ejimuti@kiu.ac.ug. ^[7] Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, Federal University of Health Sciences, Otukpo, Benue State, Nigeria. ^[8] Chemistry, IUBAT-International University of Business Agriculture & Technology, Dhaka, Bangladesh. ^[9] Centre for Excellence in Functional foods and Gastronomy Faculty of Agro-industry, Prince of Songkla University, Hat Yai, Thailand. ^[10] Department of Industrial Chemistry, College of Science, Evangel University Akaeze, Ebonyi, Nigeria. ^[11]

关键词 Cosurfactant, solubility Ornidazole self-nano emulsifying system Surfactant