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Developing and validating a comprehensive polygenic risk score to enhance keratoconus risk prediction.

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作者单位: QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia.;Faculty of Medicine, The University of Queensland, Brisbane, St Lucia, Queensland 4072, Australia. [1] Department of Genetics, University Medical Centre Groningen Medical Faculty building (building 3211) 5th floor, Antonius Deusinglaan 1 9713 AV Groningen, The Netherlands.;Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, Estonia. [2] Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, Estonia.;Eye Clinic, East Tallinn Central Hospital, Ravi street 18, 10138 Tallinn, Estonia.;Department of Ophthalmology, Emory University, 201 Dowman Dr NE, Atlanta, GA 30322, United States. [3] QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia. [4] Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart Tasmania 7000, Australia.;Centre for Eye Research Australia, University of Melbourne, Peter Howson Wing, Level 7, 32 Gisborne Street, Melbourne East Victoria 3002, Australia. [5] Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, 2 Verdun Street, Nedlands, Western Australia 6009, Australia. [6] QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland 4006, Australia.;Faculty of Medicine, The University of Queensland, Brisbane, St Lucia, Queensland 4072, Australia.;Faculty of Health, School of Biomedical Sciences, Queensland University of Technology, R Block, Kelvin Grove Campus Victoria Park Road, Kelvin Grove, Queensland 4059, Australia. [7] Estonian Genome Centre, Institute of Genomics, University of Tartu, Riia 23b, Tartu, Estonia. [8]
DOI 10.1093/hmg/ddae157
PMID 39535071
发布时间 2024-11-13
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