Gut microbiota in very early systemic sclerosis: the first case-control taxonomic and functional characterisation highlighting an altered butyric acid profile.

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第一作者： Silvia,Bellando-Randone

第一单位： Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy.;Scleroderma Unit, Azienda Ospedaliero-Universitaria Careggi (AOUC), Florence, Italy.

作者： Silvia,Bellando-Randone ^[1] ; Edda,Russo ^[2] ; Leandro,Di Gloria ^[3] ; Gemma,Lepri ^[1] ; Simone,Baldi ^[2] ; Bianca Saveria,Fioretto ^[4] ; Eloisa,Romano ^[2] ; Giulio,Ghezzi ^[5] ; Sara,Bertorello ^[2] ; Khadija,El Aoufy ^[6] ; Irene,Rosa ^[7] ; Marco,Pallecchi ^[8] ; Cosimo,Bruni ^[9] ; Francesco,Cei ^[2] ; Giulia,Nannini ^[2] ; Elena,Niccolai ^[2] ; Martina,Orlandi ^[10] ; Giulia,Bandini ^[2] ; Serena,Guiducci ^[1] ; Gian Luca,Bartolucci ^[11] ; Matteo,Ramazzotti ^[3] ; Mirko,Manetti ^[7] ; Marco,Matucci-Cerinic ^[12] ; Amedeo,Amedei ^[2]

作者单位： Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy.;Scleroderma Unit, Azienda Ospedaliero-Universitaria Careggi (AOUC), Florence, Italy. ^[1] Department of Experimental and Clinical Medicine, Section of Internal Medicine, University of Florence, Florence, Italy. ^[2] Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, Florence, Italy. ^[3] Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy. ^[4] Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy. ^[5] Department of Health Sciences, University of Florence, Florence, Italy. ^[6] Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Florence, Italy.;Department of Experimental and Clinical Medicine, Imaging Platform, University of Florence, Florence, Italy. ^[7] Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy. ^[8] Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy.;Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland. ^[9] Department of Medical and Surgical Sciences for Children, University of Modena and Reggio Emilia, Modena, Italy. ^[10] Department of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Florence, Italy. ^[11] Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS San Raffaele Hospital, Milan, Italy MatucciCerinic.Marco@hsr.it.;Vita Salute San Raffaele University, Milan, Italy. ^[12]

关键词 inflammation lipids systemic sclerosis

主题词人类(Humans);硬皮病, 系统性(Scleroderma, Systemic);女(雌)性(Female);男(雄)性(Male);病例对照研究(Case-Control Studies);中年人(Middle Aged);酪酸(Butyric Acid);成年人(Adult);RNA, 核糖体, 16S(RNA, Ribosomal, 16S);粪便(Feces);脂肪酸类, 挥发性(Fatty Acids, Volatile);细菌(Bacteria);老年人(Aged)

DOI 10.1136/rmdopen-2024-004647

PMID 39557490

发布时间 2024-12-05

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Gut microbiota in very early systemic sclerosis: the first case-control taxonomic and functional characterisation highlighting an altered butyric acid profile.

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Gut microbiota in very early systemic sclerosis: the first case-control taxonomic and functional characterisation highlighting an altered butyric acid profile.

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