Unveiling the molecular mechanisms of Danggui-Shaoyao-San against Alzheimer's disease in APP/PS1 mice via integrating proteomic and metabolomic approaches.

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第一作者： Qihui,Wu

第一单位： Clinical Research Center, Hainan Hospital, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Haikou, 570100, China. wuqh@hainmc.edu.cn.

作者： Qihui,Wu ^[1] ; Wei,Wang ^[2] ; Zhuangzi,Huang ^[3] ; Xianghao,Lin ^[4] ; Maozhong,Yao ^[3] ; Chuipu,Cai ^[5] ; Guohu,Weng ^[6] ; Yong,Gu ^[7] ; Hongying,Li ^[8] ; Jinman,Liu ^[9] ; Jiansong,Fang ^[10] ; Weirong,Li ^[11]

作者单位： Clinical Research Center, Hainan Hospital, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Haikou, 570100, China. wuqh@hainmc.edu.cn. ^[1] Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, China. ^[2] Clinical Research Center, Hainan Hospital, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Haikou, 570100, China. ^[3] School of Clinical Medicine, Hubei University of Science and Technology, Xianning, 437100, China. ^[4] Department of Computer Science, Key Laboratory of Intelligent Manufacturing Technology of Ministry of Education, Shantou University, Shantou, 515000, China. ^[5] Hainan Clinical Center for Encephalopathy of Chinese Medicine, Haikou, 571000, China. ^[6] Clinical Research Center, Hainan Hospital, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Haikou, 570100, China.;Hainan Clinical Center for Encephalopathy of Chinese Medicine, Haikou, 571000, China. ^[7] College of Traditional Chinese Medicine, Hainan Academy of Medical Sciences, Hainan Medical University, Haikou, 571000, China. ^[8] Affiliated Jiangmen TCM Hospital of Ji'nan University, Jiangmen, 529099, China. ^[9] Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, China. fangjs@gzucm.edu.cn. ^[10] Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, China. liwr@gzucm.edu.cn. ^[11]

关键词 Alzheimer’s disease Danggui-Shaoyao-San Energy metabolism Multi-omics