首页> The Journal of pharmacy and pharmacology> Roflumilast mitigates cisplatin-induced nephrotoxicity by regulating TNF-α/TNFR1/TNFR2/Fas/Caspase mediated apoptosis and inflammatory signals.

Roflumilast mitigates cisplatin-induced nephrotoxicity by regulating TNF-α/TNFR1/TNFR2/Fas/Caspase mediated apoptosis and inflammatory signals.

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第一作者： Priyal,Patel

第一单位： Department of Pharmacology, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Anand, Gujarat 388421, India.

作者： Priyal,Patel ^[1] ; Sandip,Patel ^[2] ; Yash,Patel ^[3] ; Piyush,Chudasama ^[4] ; Shailesh,Soni ^[5] ; Samir,Patel ^[6] ; Manan,Raval ^[7]

作者单位： Department of Pharmacology, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Anand, Gujarat 388421, India. ^[1] Department of Pharmacology, L.M. College of Pharmacy, Ahmedabad, Gujarat 380009, India. ^[2] Department of Clinical Pharmacy, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Anand, Gujarat 388421, India. ^[3] Department of Research and Development, Sat-Kaival Hospital Pvt. Ltd, Anand, Gujarat 388001, India. ^[4] Department of Pathology, Muljibhai Patel Urological Hospital, Nadiad, Gujarat 387002, India. ^[5] Department of Pharmaceutical Chemistry and Analysis, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Anand, Gujarat 388421, India. ^[6] Department of Pharmacognosy and Phytochemistry, Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology, Changa, Anand, Gujarat 388421, India. ^[7]

关键词 Inflammation Roflumilast apoptosis cisplatin