NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.

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作者： M Firoz,Mian ^[1] ; Sidney,Pa ^[1] ; Nuzhat,Rahman ^[1] ; Amy,Gillgrass ^[1] ; Charu,Kaushic ^[1]

作者单位： McMaster Immunology Research Centre, Department of Medicine, McMaster University, Hamilton, ON, Canada.;Department of Medicine, McMaster University, Hamilton, ON, Canada. ^[1]

关键词 DMPA IFN-γ NET-EN TNF-α herpes simplex virus type 2 mucin vaginal tract

主题词动物(Animals);女(雌)性(Female);醋酸甲羟孕酮(Medroxyprogesterone Acetate);小鼠(Mice);生殖器疱疹(Herpes Genitalis);疾病模型, 动物(Disease Models, Animal);疱疹病毒2型, 人(Herpesvirus 2, Human);炔诺酮(Norethindrone);避孕药, 女用(Contraceptive Agents, Female);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);生殖器, 女(雌)性(Genitalia, Female);阴道(Vagina);卵巢切除术(Ovariectomy)

DOI 10.3389/fimmu.2024.1427842

PMID 39569191

发布时间 2024-11-22

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Frontiers in immunology

2024年15卷

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NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.

Frontiers in immunology

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Frontiers in immunology

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NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.

Frontiers in immunology

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Frontiers in immunology

相关期刊

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