Association between homologous recombination deficiency and time to treatment failure to platinum-based chemotherapy for pancreatic cancer by using the C-CAT database.

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第一作者： Kazunaga,Ishigaki

第一单位： Department of Clinical Oncology, The University of Tokyo Hospital, Tokyo, Japan.;Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo Bunkyo-Ku, Tokyo, 113-8655, Japan.

作者： Kazunaga,Ishigaki ^[1] ; Yurie,Tokito ^[2] ; Naminatsu,Takahara ^[3] ; Hiroto,Nishio ^[2] ; Go,Endo ^[2] ; Koshiro,Fukuda ^[2] ; Kota,Ishida ^[2] ; Rintaro,Fukuda ^[2] ; Shinya,Takaoka ^[2] ; Hiroki,Oyama ^[2] ; Kensaku,Noguchi ^[2] ; Tatsunori,Suzuki ^[2] ; Tatsuya,Sato ^[2] ; Tomotaka,Saito ^[2] ; Tsuyoshi,Hamada ^[2] ; Koji,Miyabayashi ^[2] ; Yasuyoshi,Sato ^[4] ; Yousuke,Nakai ^[5] ; Hidenori,Kage ^[6] ; Katsutoshi,Oda ^[7] ; Mitsuhiro,Fujishiro ^[1]

作者单位： Department of Clinical Oncology, The University of Tokyo Hospital, Tokyo, Japan.;Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo Bunkyo-Ku, Tokyo, 113-8655, Japan. ^[1] Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo Bunkyo-Ku, Tokyo, 113-8655, Japan. ^[2] Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo Bunkyo-Ku, Tokyo, 113-8655, Japan. naminatsu.takahara@gmail.com. ^[3] Department of Clinical Oncology, The University of Tokyo Hospital, Tokyo, Japan. ^[4] Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo Bunkyo-Ku, Tokyo, 113-8655, Japan.;Department of Internal Medicine, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan. ^[5] Department of Respiratory Medicine, The University of Tokyo Hospital, Tokyo, Japan. ^[6] Department of Clinical Genomics, The University of Tokyo Hospital, Tokyo, Japan. ^[7]

关键词 Chemotherapy Comprehensive genomic profiling Homologous recombination deficiency Pancreatic cancer