首页> Therapeutic advances in gastroenterology> Effectiveness and safety outcomes after long-term (54 weeks) vedolizumab therapy for Crohn's disease: a prospective, real-world observational study including patient-reported outcomes (POLONEZ II).

Effectiveness and safety outcomes after long-term (54 weeks) vedolizumab therapy for Crohn's disease: a prospective, real-world observational study including patient-reported outcomes (POLONEZ II).

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第一作者： Ariel,Liebert

第一单位： Department of Gastroenterology and Nutritional Disorders, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland.

作者： Ariel,Liebert ^[1] ; Maria,Kłopocka ^[1] ; Agata,Michalak ^[2] ; Halina,Cichoz-Lach ^[2] ; Renata,Talar-Wojnarowska ^[3] ; Danuta,Domz Ał-Magrowska ^[3] ; Łukasz,Konecki ^[4] ; Aleksandra,Filipiuk ^[4] ; Michał,Krogulecki ^[4] ; Maria,Kopertowska-Majchrzak ^[5] ; Kamila,Stawczyk-Eder ^[6] ; Katarzyna,Waszak ^[6] ; Piotr,Eder ^[6] ; Edyta,Zagórowicz ^[7] ; Izabela,Smoła ^[8] ; Krzysztof,Wojciechowski ^[9] ; Szymon,Drygała ^[10]

作者单位： Department of Gastroenterology and Nutritional Disorders, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Bydgoszcz, Poland. ^[1] Department of Gastroenterology, Medical University of Lublin, Lublin, Poland. ^[2] Department of Digestive Tract Diseases, Medical University of Łódź, Łódź, Poland. ^[3] Department of Gastroenterology, Military Institute of Medicine, Warsaw, Poland. ^[4] Department of Internal Diseases, General Hospital, Mie˛dzychód, Poland. ^[5] Department of Gastroenterology, Dietetics, and Internal Diseases, Poznan University Clinical Hospital, Poznań University of Medical Sciences, Poznań, Poland. ^[6] Department of Gastroenterology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.;Department of Gastroenterology, Hepatology and Clinical Oncology, Medical Center of Postgraduate Education, Warsaw, Poland. ^[7] Department and Clinic of Gastroenterology, Hepatology and Internal Medicine, Faculty of Medicine, Wrocław Medical University, Wrocław, Poland. ^[8] Department of Internal Diseases, The Independent Public Health Care Center, Tarczyn, Poland. ^[9] Szymon Drygała Takeda Pharma Sp. z.o.o., St. Prosta 68, Warsaw, Mazovia Province 00-838, Poland. ^[10]

关键词 Crohn’s disease Inflammatory Bowel Disease Questionnaire Inflammatory Bowel Disease-Fatigue self-assessment scale anti-integrin monoclonal antibody patient-reported outcomes quality of life real-world prospective analysis response durability steroid-free remission vedolizumab

DOI 10.1177/17562848241293938

PMID 39575158

发布时间 2026-03-20

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