首页> Cancer cell> Elucidating acquired PARP inhibitor resistance in advanced prostate cancer.

Elucidating acquired PARP inhibitor resistance in advanced prostate cancer.

导出 OA

翻译打印收藏纠错

第一作者： George,Seed

第一单位： The Institute of Cancer Research, London, UK.

作者： George,Seed ^[1] ; Nick,Beije ^[2] ; Wei,Yuan ^[1] ; Claudia,Bertan ^[1] ; Jane,Goodall ^[1] ; Arian,Lundberg ^[1] ; Matthew,Tyler ^[1] ; Ines,Figueiredo ^[1] ; Rita,Pereira ^[1] ; Chloe,Baker ^[1] ; Denisa,Bogdan ^[1] ; Lewis,Gallagher ^[1] ; Jan-Phillipp,Cieslik ^[3] ; Semini,Greening ^[1] ; Maryou,Lambros ^[1] ; Rui,Neves ^[3] ; Lorena,Magraner-Pardo ^[1] ; Gemma,Fowler ^[1] ; Berni,Ebbs ^[1] ; Susana,Miranda ^[1] ; Penny,Flohr ^[1] ; Diletta,Bianchini ^[4] ; Pasquale,Rescigno ^[1] ; Nuria,Porta ^[1] ; Emma,Hall ^[1] ; Bora,Gurel ^[1] ; Nina,Tunariu ^[4] ; Adam,Sharp ^[2] ; Stephen,Pettit ^[1] ; Nikolas H,Stoecklein ^[3] ; Shahneen,Sandhu ^[4] ; David,Quigley ^[5] ; Christopher J,Lord ^[1] ; Joaquin,Mateo ^[6] ; Suzanne,Carreira ^[1] ; Johann,de Bono ^[7]

作者单位： The Institute of Cancer Research, London, UK. ^[1] The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, London, UK. ^[2] Heinrich Heine University, Düsseldorf, Germany. ^[3] The Royal Marsden NHS Foundation Trust, London, UK. ^[4] UCSF, San Francisco, CA, USA. ^[5] Vall d'Hebron Institute of Oncology, Barcelona, Spain. ^[6] The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, London, UK. Electronic address: johann.de-bono@icr.ac.uk. ^[7]

关键词 DNA repair PARP inhibition cfDNA genomics prostate cancer reversion

医学主题词人类(Humans);男(雄)性(Male);抗药性, 肿瘤(Drug Resistance, Neoplasm);BRCA2蛋白质(BRCA2 Protein);突变(Mutation);酞嗪类(Phthalazines)

DOI 10.1016/j.ccell.2024.10.015

PMID 39577422

发布时间 2025-09-10

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交