首页> Journal of neuro-oncology> Patient-derived glioma organoids real time identification of IDH mutation, 1p/19q-codeletion and CDKN2A/B homozygous deletion with differential ion mobility spectrometry.

Patient-derived glioma organoids real time identification of IDH mutation, 1p/19q-codeletion and CDKN2A/B homozygous deletion with differential ion mobility spectrometry.

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第一作者： Ismaïl,Hermelo

第一单位： Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland. ismail.hermelo@gmail.com.;Department of Neurosurgery and Tays Cancer Center, Tampere University Hospital and Tampere University, Tampere, Finland. ismail.hermelo@gmail.com.;Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. ismail.hermelo@gmail.com.

作者： Ismaïl,Hermelo ^[1] ; Ilkka,Haapala ^[2] ; Meri,Mäkelä ^[3] ; Dafne,Jacome Sanz ^[4] ; Anton,Kontunen ^[3] ; Markus,Karjalainen ^[3] ; Philipp,Müller ^[5] ; Kai,Lehtimäki ^[2] ; Matti,Nykter ^[6] ; Juhana,Frösén ^[2] ; Hannu,Haapasalo ^[7] ; Antti,Roine ^[3] ; Niku,Oksala ^[8] ; Kristiina,Nordfors ^[9] ; Antti,Vehkaoja ^[5] ; Joonas,Haapasalo ^[10]

作者单位： Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland. ismail.hermelo@gmail.com.;Department of Neurosurgery and Tays Cancer Center, Tampere University Hospital and Tampere University, Tampere, Finland. ismail.hermelo@gmail.com.;Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. ismail.hermelo@gmail.com. ^[1] Department of Neurosurgery and Tays Cancer Center, Tampere University Hospital and Tampere University, Tampere, Finland. ^[2] Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.;Olfactomics Ltd., Tampere, Finland. ^[3] Department of Neurosurgery and Tays Cancer Center, Tampere University Hospital and Tampere University, Tampere, Finland.;Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. ^[4] Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. ^[5] Prostate Cancer Research Center, Faculty of Medicine and Health Technology, Tampere University and Tampere University Hospital, Tampere, Finland.;Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. ^[6] Fimlab Laboratories Ltd., Tampere, Finland. ^[7] Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.;Olfactomics Ltd., Tampere, Finland.;Centre for Vascular Surgery and Interventional Radiology, Tampere University Hospital, Tampere, Finland. ^[8] Department of Pediatric Hematology and Oncology and Tays Cancer Center, Tampere University Hospital, Tampere, Finland.;Tampere Center for Child, Adolescent, and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland. ^[9] Department of Neurosurgery and Tays Cancer Center, Tampere University Hospital and Tampere University, Tampere, Finland. joonas.haapasalo@pirha.fi.;Fimlab Laboratories Ltd., Tampere, Finland. joonas.haapasalo@pirha.fi. ^[10]

关键词 1p/19 co-deletion CDKN2A/B homozygous loss Differential mobility spectrometry IDH mutation Linear discriminant analysis Patient-derived glioma organoids