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Ileal microbial microbiome and its secondary bile acids modulate susceptibility to nonalcoholic steatohepatitis in dairy goats.

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第一作者： Yue,Wang

第一单位： College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.;Faculty of Land and Food Systems, the University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.;Key Laboratory of Livestock Biology, Northwest A&F University, Yangling, Shaanxi, China.

作者： Yue,Wang ^[1] ; Xiaodong,Chen ^[2] ; Sharon A,Huws ^[3] ; Guanghao,Xu ^[4] ; Jing,Li ^[4] ; Jianrong,Ren ^[4] ; Jingyi,Xu ^[4] ; Le Luo,Guan ^[5] ; Junhu,Yao ^[6] ; Shengru,Wu ^[7]

作者单位： College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.;Faculty of Land and Food Systems, the University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.;Key Laboratory of Livestock Biology, Northwest A&F University, Yangling, Shaanxi, China. ^[1] College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.;College of Animal Science and Technology, Ningxia University, Yinchuan, China.;Key Laboratory of Livestock Biology, Northwest A&F University, Yangling, Shaanxi, China. ^[2] Institute of Global Food Security, School of Biological Sciences, Queen's University Belfast, 19 Chlorine Gardens, Belfast, Northern Ireland, BT9 5DL, UK. ^[3] College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.;Key Laboratory of Livestock Biology, Northwest A&F University, Yangling, Shaanxi, China. ^[4] Faculty of Land and Food Systems, the University of British Columbia, Vancouver, BC, V6T 1Z4, Canada. leluo.guan@ubc.ca. ^[5] College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China. yaojunhu2008@nwafu.edu.cn.;Key Laboratory of Livestock Biology, Northwest A&F University, Yangling, Shaanxi, China. yaojunhu2008@nwafu.edu.cn. ^[6] College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China. wushengru2013@163.com.;Key Laboratory of Livestock Biology, Northwest A&F University, Yangling, Shaanxi, China. wushengru2013@163.com. ^[7]

关键词 Dairy goats Ileal microbiome Intrahepatic TH17 cells and Treg cells Nonalcoholic steatohepatitis susceptibility Secondary bile acids