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Depletion of regulatory T cells enhances the T cell response induced by the neoantigen vaccine with weak immunogenicity.

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作者: Ruichen,Huang [1] ; Qiao,Zhou [2] ; Jiajun,Liu [3] ; Yang,Xia [1] ; Yang,Jiao [1] ; Bi,Zhao [1] ; Tangtao,Feng [1] ; Haosu,Zhou [1] ; Xiuyan,Song [1] ; Hao,Qin [4] ; Jun,Wang [4] ; Lan,Cheng [1] ; Yunye,Ning [1] ; Qinying,Sun [1] ; Yanfang,Liu [5] ; Xiaoping,Su [6] ; Yuchao,Dong [7] ; Wei,Zhang [8]
作者单位: Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China. [1] Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, PR China. [2] Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, PR China. [3] Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China; Center of Critical Care Medicine, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China. [4] Department of Pathology, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China. [5] School of Basic Medicine, Wenzhou Medical University, Wenzhou, 325000, China; Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China; Zhejiang Key Laboratory of Intelligent Cancer Biomarker Discovery and Translation, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325035, China. Electronic address: bloooge@163.com. [6] Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China. Electronic address: dongyc1020@126.com. [7] Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China; Center of Critical Care Medicine, the First Affiliated Hospital of Second Military Medical University, Shanghai, 200433, PR China. Electronic address: zhangweismmu@126.com. [8]
DOI 10.1016/j.neo.2024.101088
PMID 39579711
发布时间 2024-12-18
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