Alginate from <i>Ericaria crinita</i> Possesses Antioxidant Activity and Attenuates Systemic Inflammation via Downregulation of Pro-Inflammatory Cytokines.

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作者： Paolina,Lukova ^[1] ; Vesela,Kokova ^[2] ; Alexandra,Baldzhieva ^[3] ; Marianna,Murdjeva ^[3] ; Plamen,Katsarov ^[4] ; Cédric,Delattre ^[5] ; Elisaveta,Apostolova ^[6]

作者单位： Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[1] Department of Pharmacology, Toxicology, and Pharmacotherapy, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[2] Department of Medical Microbiology and Immunology "Prof. Dr. Elissay Yanev", Faculty of Medicine, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria.;Research Institute at Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[3] Research Institute at Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria.;Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[4] Clermont Auvergne INP, CNRS, Institut Pascal, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.;Institut Universitaire de France (IUF), 1 rue Descartes, 75005 Paris, France. ^[5] Department of Pharmacology, Toxicology, and Pharmacotherapy, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria.;Research Institute at Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[6]

关键词 Cystoseira crinita Ericaria crinita IL-1β Il-6 TNF-α alginate anti-inflammatory effect antioxidant effect cytokines