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首页> Cell communication and signaling : CCS> A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice.

A ketogenic diet alleviates the apoptosis of granulosa cells by inhibiting the activation of cGAS-STING signaling pathway in PCOS mice.

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作者： Bining,Zhao ^[1] ; Haowen,Wu ^[1] ; Qiyang,Yao ^[1] ; Wenpei,Bai ^[2] ; Jihong,Kang ^[3]

作者单位： Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China.;Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, No.38 Xueyuan Rd, Haidian District, Beijing, 100191, China. ^[1] Department of Obstetrics and Gynecology, Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing, 100038, China. baiwp@bjsjth.cn. ^[2] Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China. kangjihong@bjmu.edu.cn.;Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University Health Science Center, No.38 Xueyuan Rd, Haidian District, Beijing, 100191, China. kangjihong@bjmu.edu.cn. ^[3]

关键词 Apoptosis Hyperandrogenemia Inflammation Ketogenic diet Mitochondrial dysfunction Polycystic ovary syndrome cGAS-STING pathway

主题词动物(Animals);女(雌)性(Female);多囊卵巢综合征(Polycystic Ovary Syndrome);信号传导(Signal Transduction);粒层细胞(Granulosa Cells);细胞凋亡(Apoptosis);膜蛋白质类(Membrane Proteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);核苷酸基转移酶类(Nucleotidyltransferases);疾病模型, 动物(Disease Models, Animal);睾酮(Testosterone)

DOI 10.1186/s12964-024-01939-6

PMID 39604996

发布时间 2024-11-30

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Cell communication and signaling : CCS

Cell communication and signaling

2024年22卷1期

568页

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